Results 341 to 350 of about 1,395,710 (388)

Synthesis and 64Cu‐Radiolabeling Strategies of Small Organic Radioconjugates Based on the AMD070 Scaffold

open access: yesChemMedChem, EarlyView.
Two novel 64Cu‐radioconjugates have been prepared, based on the AMD070 scaffold as a targeting unit and cyclam‐based te1pa chelator, for future applications in positron emission tomography imaging. Synthesis of ligands and their 64Cu‐radiolabeling are described herein.
Marie M. Le Roy   +5 more
wiley   +1 more source

Novel Para‐Phenylenediamine‐Based Derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization

open access: yesChemMedChem, EarlyView.
ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone   +17 more
wiley   +1 more source

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