Results 111 to 120 of about 60,678 (260)

The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma

Immunology &Cell Biology, EarlyView.
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald, Matthew Drill, Padmakrishnan C. Jayakrishnan, Richard P. Sequeira, Terence J. O'Brien, Rosalind L. Jeffree, Mastura Monif   +6 more
wiley   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta, Tong Wang, Susmita, Ditte Marie L. Saunte, Roderick Hay, Vincent Piguet   +5 more
wiley   +1 more source

Efficacy, Safety, and Pharmacokinetics of Upadacitinib Among Patients in East Asia With Moderately to Severely Active Ulcerative Colitis: A Post Hoc Subanalysis of Randomized Phase 3 Studies

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Upadacitinib, a selective Janus kinase 1 inhibitor, is approved to treat moderately to severely active ulcerative colitis (UC). This post hoc subanalysis evaluated the efficacy, safety, and pharmacokinetics of upadacitinib in patients in East Asia. Methods U‐ACHIEVE (UC1; NCT02819635) and U‐ACCOMPLISH (UC2; NCT03653026) were
Shu Chen Wei, Hiroshi Nakase, Byong Duk Ye, Kang Chao, Hsin‐Yun Wu, Jason Eccleston, Xuan Yao, Hannah Palac, Mohamed‐Eslam F. Mohamed, Ana Victoria Ponce‐Bobadilla, Smitha Suravaram, Elena Marced Barrachina, Tadakazu Hisamatsu, Xiang Gao   +13 more
wiley   +1 more source

The Association of Pretransplant CD4 Count With Post‐Kidney Transplant Infectious Outcomes Among Persons With HIV

Transplant Infectious Disease, EarlyView.
In this multi‐center study comparing persons with HIV with pre‐kidney transplant CD4 < 350 cells/µL to those with ≥ 350 cells/µL, we found no difference in relative risk of infection in the first year‐post kidney transplant, 5‐year graft survival, and 5‐year overall survival.
Rebecca H. Burns, Sara Booth, Christin Rogers Marks, Christine M. Durand, Jonathan Hand, Maheen Z. Abidi, Maricar Malinis, Brittany Barnaba, Martha Pavlakis, Douglas Krakower, Carolyn D. Alonso, Audrey Le‐Mahajan   +11 more
wiley   +1 more source

Cytomegalovirus–Cell‐Mediated Immunity Assays for the Prevention and Management of Cytomegalovirus in Transplant Recipients and Patients Receiving Cellular Therapies

Transplant Infectious Disease, EarlyView.
This review summarizes the emerging role of CMV‐specific cell‐mediated immunity assays in CMV risk prediction and individualized prevention strategies across SOT, HCT, and CAR‐T settings. ABSTRACT CMV cell–mediated immunity (CMV–CMI) testing has emerged as a promising tool to refine CMV risk stratification and inform prevention strategies in transplant
Elisa Ruiz‐Arabi, Madeleine R. Heldman, Laurie D. Snyder, Oriol Manuel, Eleftheria Kampouri   +4 more
wiley   +1 more source

The lymphocyte function of allogeneic peripheral blood stem cell grafts is associated with relapse and cytomegalovirus reactivation

Transfusion, EarlyView.
Abstract Background Allogeneic hematopoietic stem cell transplantation (HSCT) is a treatment primarily for hematological malignancies. Infections, relapse, and graft versus host disease (GvHD) are some of the most common adverse events following HSCT. We aimed to evaluate whether the lymphocyte function of the stem cell graft was associated with these ...
Anna Söderström, Tengyu Wang, Johan Törlén, Hannes Lindahl, Davide Valentini, Stephan Mielke, Klara Asplund Högelin, Rebecca Axelsson Robertson, Michael Uhlin   +8 more
wiley   +1 more source

Disseminated Cryptococcosis under Fingolimod Therapy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Sven C. Engler, Morna F. Schmidt, Ana Ortins‐Pina, David Kluwig, Amir S. Yazdi   +4 more
wiley   +1 more source

Clinical Behaviour and Outcome of Pelvic Osteosarcoma in Dogs: A Retrospective Multicentre Analysis of 74 Cases (2007–2025)

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Although osteosarcoma is the most common primary bone tumour in dogs, involvement of the pelvic bones is rare. The aim of the present study was to describe clinical presentation, identify possible prognostic factors, and evaluate outcomes in dogs diagnosed with pelvic osteosarcoma.
Csilla Fejös, Felicitas Czichon, Maureen Griffin, Natalie Grillo, Quentin Fournier, Michelle L. Oblak, Mikaela Eng‐Toogood, Michael Kent, Isabelle Desmas‐Bazelle, Miriam Kleiter, Laura Marconato, Katie McNaught, Simona Vincenti, Carmit Chalfon, Petros Odatzoglou, Carla Rohrer Bley   +15 more
wiley   +1 more source

The Common Causes of Lymphopenia [PDF]

Journal of Clinical Pathology, 1950
openaire   +2 more sources

Infection with the Neorickettsial Organism Stellantchasmus falcatus Agent in an Arctic Fox (Vulpes lagopus)

Veterinary Clinical Pathology, EarlyView.
ABSTRACT A 1‐year‐old female‐intact arctic fox (Vulpes lagopus) presented for diarrhea, lethargy, severe thrombocytopenia, and hyperbilirubinemia. Blood film evaluation revealed intracytoplasmic coccoid bacteria within moderate numbers of leukocytes consistent with infection by a rickettsial organism.
Jeremy P. Bessett, Alexis G. Davidson, Alyssa M. Scagnelli, Kristen R. Friedrichs   +3 more
wiley   +1 more source