Results 41 to 50 of about 179,557 (197)

Lymphoplasmacytic Lymphoma and Waldenström Macroglobulinemia

Archives of Pathology & Laboratory Medicine, 2013
Lymphoplasmacytic lymphoma (LPL) is a low-grade, B-cell neoplasm composed of small lymphocytes, plasmacytoid lymphocytes, and plasma cells that typically involve the bone marrow, and it is associated with an immunoglobulin M (IgM) gammopathy. The definition of Waldenström macroglobulinemia (WM) and its relationship to LPL has been confusing in the past.
Nadia, Naderi, David T, Yang
openaire   +2 more sources

Molecular Pathogenesis of MALT lymphoma [PDF]

, 2011
Mucosa associated lymphoid tissue (MALT) lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1, which commonly activate the NF-κB pathway.

core   +2 more sources

Bing-Neel Syndrome Case Report: A Previously Undocumented IgG Variant with MRI, PET/CT, and PET/MRI Imaging

Case Reports in Hematology, 2016
Waldenstrom’s macroglobulinaemia is the most commonly reported subtype of lymphoplasmacytic lymphoma (LPL); it is characterised by IgM secretion. Neurological complications are common usually as a result of hyperviscosity.
Daniel Halperin, Simon Hallam, Athar Haroon, Tom Butler, Samir Agrawal   +4 more
doaj   +1 more source

Poorly differentiated lung adenocarcinomas with concurrent ALK and CD30 expression: a diagnostic pitfall mimicking ALK‐positive anaplastic large‐cell lymphoma

Histopathology, EarlyView.
Poorly differentiated lung adenocarcinomas with concurrent anaplastic lymphoma kinase (ALK) and CD30 expression closely mimic ALK‐positive anaplastic large‐cell lymphoma, creating a significant diagnostic pitfall. Accurate classification requires comprehensive integration of clinical, radiologic, morphologic, immunophenotypic and molecular findings ...
Jietian Jin, Wenjian Cen, Qin Yan, Yangshan Chen, Chaoyun Huang, Yanfeng Feng, Neng Jiang   +6 more
wiley   +1 more source

Vitamin D3 receptor is highly expressed in Hodgkin's lymphoma [PDF]

, 2012
Background: Hodkin s lymphoma is one of the most frequent lymphoma in western world. Despite an overall good prognosis some patients suffer relapsing tumors which are difficult to cure.
Renné Christoph, Benz Alexander H, Hansmann Martin L, Christoph, Renné, Benz, Alexander, Hansmann, Martin-Leo   +5 more
core   +1 more source

Waldenstrom macroglobulinemia involving the superior rectus muscle

American Journal of Ophthalmology Case Reports, 2018
Purpose: We present the first reported case of Waldenstrom macroglobulinemia in the right superior rectus causing diplopia. Observations: A 72-year-old man with a 6-month history of untreated asymptomatic Waldenstrom macroglobulinemia presented with 2 ...
J.B. Hellman, G.J. Harocopos, L.K. Lin
doaj   +1 more source

Investigation of IgM Monoclonal Paraprotein in Bone Marrow Aspiration: The Role of Immunophenotyping by Flow Cytometry in Selecting Cases for Molecular Testing for the p.MYD88 L265P Point Mutation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Flow cytometry and real‐time quantitative polymerase chain reaction (qRT‐PCR) for MYD88 mutations (MYD88mt) are routinely performed on bone marrow aspirates during the diagnostic evaluation of IgM monoclonal paraproteinemia. The potential predictive value of immunophenotypic findings for molecular results, however, remains to be ...
Georgios Boutsikas, Konstantinos Agiannitopoulos, Elisavet Kouvidi, Myrto Katraki, Athanasios Papatheodorou, Anna Roussou, Nikolaos Paschalidis, Theodoros P. Vassilakopoulos, Ioannis Anagnostopoulos, Dimitra Sasaroli, Aglaia Dimitrakopoulou   +10 more
wiley   +1 more source

Waldenström Macroglobulinemia Diagnosed by Ultrasonography‐Guided Biopsy of the Right Perinephric Tumor

IJU Case Reports
Introduction Waldenström macroglobulinemia is a low‐grade B‐cell lymphoma characterized by lymphoplasmacytic lymphoma infiltration of the bone marrow and immunoglobulin M (IgM) protein.
Shingo Morinaga, Shigeyuki Aoki, Motoi Tobiume, Genya Nishikawa, Fusako Higuchi, Yuusuke Ikenohata, Manabu Honda, Hiroe Kubo, Tomoko Sawada, Yoshiaki Yamada   +9 more
doaj   +1 more source

MyD88‐Family Adaptors: Compartmentalised Signalling and Non‐Immune Functions

Immunology, EarlyView.
MyD88‐family adaptors coordinate receptor‐ and compartment‐specific innate immune signalling across plasma membrane and endosomal pathways. At the plasma membrane, TIRAP/MAL supports MyD88‐dependent signalling downstream of TLR2 and TLR4, whereas endosomal TLR7, TLR8 and TLR9 recruit MyD88 directly.
Seshu Vardhan Pothabathula, Saurabh Mishra, Pugazhendhi Kannan, Annette Bellar, Amy Attaway, Nicole Welch, Srinivasan Dasarathy   +6 more
wiley   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, Volume 101, Issue 10, Page 2632-2651, October 2026.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source