Results 91 to 100 of about 50,534 (301)

Enhanced stability of siRNA-loaded lipid nanoparticles during lyophilization via acetyl-arginine and disaccharides

International Journal of Pharmaceutics: X
RNA-loaded lipid nanoparticles (LNPs) are highly sensitive to temperature fluctuations, which present significant challenges for storage and transportation.
Ki Hyun Kim, Arun Mainali, Seung Hyun Pih, Hun Soon Jung, Hye Jeong Kim, Nam Ah Kim, Seong Hoon Jeong   +6 more
doaj   +1 more source

Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis

Advanced Materials, EarlyView.
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne, Julian S. Hertel, André Delavault, Judith Felk, Martin Peng, Lara Reuber, Felix Ott, Kim Wanner, Marc F. Münker, Adrian Neukirch, Alexei Kiselev, Kersten S. Rabe, Christof M. Niemeyer   +12 more
wiley   +1 more source

Lyophilization of Semiconducting Polymer Dot Bioconjugates

, 2016
Semiconducting polymer dot (Pdot) bioconjugates are a new class of ultrabright fluorescent probes. Here, we report a procedure for lyophilizing Pdot bioconjugates so that they successfully retain their optical properties, colloidal stability, and cell ...
Daniel T. Chiu (1313448), Changfeng Wu (1340484), Fangmao Ye (1340490), Wei Sun (93580), Maria E. Gallina (1961992), Jiangbo Yu (522108)   +5 more
core   +1 more source

A Thermoreversible Gelation Pathway to Plant Cuticle‐Inspired Biopolymer Aerogel Monoliths Based on Network‐Spherulitic Crystal Assemblies

Advanced Materials, EarlyView.
To address functionality limitations in plant‐based and industrially compostable polymer aerogels, this work introduces bio‐inspired aerogels with broadened functionality. Inspired by functional plant tissues, lightweight biopolymer aerogels based on exclusively stereocomplex crystals are fabricated, featuring hierarchically macro‐/meso‐porous ...
Anthony V. Tuccitto, Zeineb Ben Rejeb, Rafaela Aguiar, Nello D. Sansone, Sumaiya Farzana, Isaac Ali, Jun Uk Lee, Daniel J. Davidson, Ailsa K. Edward, Chul B. Park, Patrick C. Lee   +10 more
wiley   +1 more source

Lyophilization and stability of antibody-conjugated mesoporous silica nanoparticle with cationic polymer and PEG for siRNA delivery

International Journal of Nanomedicine, 2018
Worapol Ngamcherdtrakul,1,2,* Thanapon Sangvanich,1,* Moataz Reda,1 Shenda Gu,1 Daniel Bejan,2 Wassana Yantasee1,2 1Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA; 2Nanomedicine Research Unit, PDX ...
Ngamcherdtrakul W, Sangvanich T, Reda M, Gu S, Bejan D, Yantasee W   +5 more
doaj  

Modeling the Effects of Osmotic Dehydration Pretreatment Parameters and Lyophilization Kinetics on Mass Transfer and Selected Nutritive Parameters of Peaches [PDF]

, 2022
The effects of the osmodehydration pretreatment parameters on successive lyophilization mass transfer kinetics of the peaches, dehydrated in the combined dehydration process, were investigated and mathematically modelled.
Filipović, Jelena, Knežević, Violeta, Filipović, Vladimir, Vujačić, Vesna, Nićetin, Milica, Lončar, Biljana   +5 more
core  

Phase‐Engineered MoS2 Quantum Monolayer Catalysts

Advanced Materials, EarlyView.
A new type of catalyst model—phase‐engineered MoS2 quantum‐monolayer catalyst (∼0.8 nm thick, < 6 nm in the lateral size; switchable freely among metallic 1T, semiconducting 2H, and a hybrid phase of metallic‐semiconducting 1T‐2H)—is reported. It can efficiently and stably drive photochemical H2, syngas and ammonia synthesis as a catalyst or co ...
Ruijie Yang, Yingying Fan, Lillian Pernitsky, Mojtaba Ebrahimian Mashhadi, Ningxin Chen, Md. Mehadi Hassan, Zheng Li, Heng Zhao, Liang Mei, Zhiyuan Zeng, Zhangxing Chen, Jinguang Hu, Qingye Lu   +12 more
wiley   +1 more source

Garlic, Cilantro and Chlorella’s Effect on Kidney Histoarchitecture Changes in Cd-intoxicated Prussian carp (Carassius gibelio)

Scientific Papers Animal Science and Biotechnologies, 2023
Natural chelators from some natural sources have been shown their detox heavy metals ability in human and animals. So the present study was carried out to histological compare the aspect of kidney tissue of Prussian carp’s specimens, subjected to chronic
Marioara Nicula, Gabi Dumitrescu, Nicolae Păcală, Lavinia Ștef, Camelia Tulcan, Monica Dragomirescu, Ioan Bencsik, Silvia Patruica, Dorel Dronca, Liliana Petculescu-Ciochina, Eliza Simiz, Ioan Peț, Adela Marcu, Ioan Caraba   +13 more
doaj  

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Research Concerning Use of Long-Term Preservation Techniques for Microorganisms

Scientific Papers Animal Science and Biotechnologies, 2023
From the large number of methods used for storage of microorganisms, the more effective methods are long-term cryopreservation and lyophilization. The temperature change rate, controls transport of water around cell membranes and indirectly likelihood of
Adriana Criste, Mihaela Giuburuncă, Octavian Negrea, Sorin Dan, Marius Zăhan   +4 more
doaj