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Lyophilization of Vaccines

2003
However effective a therapeutic agent may appear during clinical trials, its full potential as a marketable product can only be assured if the material can be stored and distributed in a stabilized form. This is particularly the case with labile biologlcals, such as attenuated vaccines, especially when these products need to be transported in tropical ...
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Lyophilization of Proteins

2007
This chapter describes the methods that can be applied to successfully freeze-dry proteins. Laboratory applications are given at small scale, typified by the purification of a protein intermediate as part of the analytical characterization of a protein, and at intermediate scale, as illustrated by the pilot development of a lyophilized protein ...
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Lyophilization of Human Cytomegaloviruses

Pathologia et Microbiologia, 2008
Lyophilization of CMV strains was performed at O°C or at 25°C with or without the addition of Parke, Davis additive. Dried viral preparations were thereafter stored at 4°C or at -20°C and tested for infectivity. The results of experiments have shown that CMV can be lyophilized at O°C with little or no loss of infectivity.
M, Jung, U, Krech
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Survival of lyophilized yeasts

Medical Mycology, 1962
Some members of the genus Candida and genus Saccharomyces are freeze-dried by a relatively new method, which is described in full. Stability of the desiccates is measured by colony counts and tested by exposure to 100°C. and long term storage at room temperature. An attempt is made to correlate the survival under both conditions.
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Refrigerated storage of lyophilized and rehydrated, lyophilized human red cells

Transfusion, 1993
Human red cells (RBCs) were collected in CPDA‐1 and then freeze‐dried in lyoprotective solution. The lyophilized RBCs were then stored at ‐20 degrees C for 7 days. At the end of the storage period, the lyophilized RBCs were rehydrated and washed in dextrose saline.
S O, Sowemimo-Coker   +3 more
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Preservation of Bacteria by Lyophilization

1961
Publisher Summary This chapter describes the preservation of bacteria by lyophilization. Lyophilization, or freeze-drying, is a term applied to the procedure of freezing and subliming water from frozen preparations. “Lyophil method” is specifically applied to the condensation of water, sublimed from frozen preparations, on a cold surface as distinct ...
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History of Lyophilization

2015
Lyophilization, also known as freeze-drying, is a process known from the ancient times for preserving material by dehydrating the sample, which includes first freezing the sample and then drying under a vacuum at very low temperatures. This chapter covers its origin, definition, and key historical events that led to the development of modern day freeze-
Dushyant Varshney, Manmohan Singh
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Lyophilization Apparatus

Science, 1945
A F, Pomes, G W, Irving
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