Results 271 to 280 of about 97,922 (330)

Polysaccharide Hydrogels Doped with MXenes for Possible Biomedical Applications. [PDF]

Molecules
Suchorowiec K, Kasznik J, Stepura A, Omastová M, Pielichowska K.   +4 more
europepmc   +1 more source

Biomanufacturing and Curcumin-Loading of Human Choroid Plexus Organoid-Derived Extracellular Vesicles from a Vertical-Wheel Bioreactor to Alleviate Neuro-Inflammation. [PDF]

Biomedicines
Ene J, Muok L, Gonzalez V, Sanchez N, Nathani A, Syed F, Liu ZL, Singh M, Driscoll T, Li Y.   +9 more
europepmc   +1 more source

Development of lyophilized mRNA-LNPs with high stability and transfection efficiency in specific cells and tissues. [PDF]

Regen Biomater
Wang T, Yu T, Li W, Chen J, Cheng S, Tian Z, Sung TC, Higuchi A.   +7 more
europepmc   +1 more source

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Lyophilization

2020
Due to the thermolability of food and pharmaceutical products the drying process cannot be performed at high temperature; lyophilization replaces then standard drying units taking advantage of sublimation instead of evaporation. Being freeze drying a batch operation, a suitable model is used to assess the operating residence time for given operating ...
Di Pretoro A., Manenti F.
openaire   +3 more sources

Lyophilization of Molecular Biology Reactions - A Review.

Mini-Reviews in Medical Chemistry, 2022
Molecular biology is a widely used and widespread technique in research and as a laboratory diagnostic tool, aiming at the investigation of targets of interest from the obtainment, identification, and analysis of genetic material.
Nayra Oliveira Prado, Larissa Araújo Lalli, Lucas Blanes, D. Zanette, M. N. Aoki   +4 more
semanticscholar   +1 more source

Lyophilization‐Free Engineering of Polyelectrolyte Monolith by an Ice‐Dissolving‐Complexation Method

Advanced Functional Materials, 2021
Ice templating is a versatile strategy for structural engineering of hydrophilic polymers and composites, yet the removal of ice templates requires lengthy lyophilization, and the prepared materials need further crosslinking for use in water.
Yunxia Ni, Xiaohong Zhou, J. Gong, Longjian Xue, Qiang Zhao   +4 more
semanticscholar   +1 more source

Determination of 38 pharmaceuticals and personal care products in water by lyophilization combined with liquid chromatography-tandem mass spectrometry.

Analytical Methods, 2021
A convenient, effective, and low-cost method was developed for the determination of 38 pharmaceuticals and personal care products (PPCPs), including 19 antibiotics in surface water samples by lyophilization combined with liquid chromatography-tandem ...
Yiqing Zhang, Lifeng Lin, Yan Li, Qiaoting Zeng, Shanshan Guo, François Nkinahamira, Chang-Ping Yu, Qian Sun   +7 more
semanticscholar   +1 more source

Lyophilization of Small-Molecule Injectables: an Industry Perspective on Formulation Development, Process Optimization, Scale-Up Challenges, and Drug Product Quality Attributes

AAPS PharmSciTech, 2020
Lyophilization is a pivotal manufacturing process to obtain a stable drug product that is unstable as a ready-to-use formulation. Some formulations may require the addition of drug-specific excipients such as stabilizers, buffers, and bulking agents to ...
Arun Butreddy, N. Dudhipala, Karthik Yadav Janga, Rajendra Prasad Gaddam   +3 more
semanticscholar   +1 more source

Design and lyophilization of mRNA-encapsulating lipid nanoparticles.

International journal of pharmaceutics
The remarkable success of two FDA-approved mRNA-encapsulating vaccines (Comirnaty® and Spikevax®) indicated the importance of lipid nanoparticles (LNPs) delivery systems in clinical use.
Ting Wang, Tao Yu, Wanqi Li, Qian Liu, Tzu-Cheng Sung, Akon Higuchi   +5 more
semanticscholar   +1 more source