Optimal amino acid system for early embryo development in sows based on response surface methodology and high-throughput screening cell models. [PDF]
Wang X+14 more
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YEATS2: a novel cancer epigenetic reader and potential therapeutic target. [PDF]
Ji K+5 more
europepmc +1 more source
Role of lysine lactylation in neoplastic and inflammatory pulmonary diseases (Review). [PDF]
Wang S, Zheng H, Zhao J, Xie J.
europepmc +1 more source
The Gcn5 lysine acetyltransferase mediates cell wall remodeling, antifungal drug resistance, and virulence of <i>Candida auris</i>. [PDF]
Chauhan M+6 more
europepmc +1 more source
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Lysine acetyltransferases and lysine deacetylases as targets for cardiovascular disease
Nature Reviews Cardiology, 2019Lysine acetylation is a conserved, reversible, post-translational protein modification regulated by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs; also known as histone deacetylases (HDACs)) that is involved in many cellular signalling pathways and diseases. Studies in animal models have revealed a regulatory role of reversible lysine
Peng Li, J. Ge, Hua Li
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Lysine−Bisglycidol Conjugates as Novel Lysine Cationic Surfactants [PDF]
The synthesis of a novel class of lysine-based cationic amphiphilic derivatives of the type N(epsilon),N(epsilon)'-bis(n-acyloxypropyl)-l-lysine methyl ester salts combining several hydroxyl functions and aliphatic chains of 12 or 14 carbon atoms is described. The compounds have one, two, three, and four alkyl chains.
Pinazo Gassol, Aurora+5 more
openaire +3 more sources
Formation of thymine-lysine and cytosine-lysine adducts in DNA-lysine photoconjugate
Journal of Photochemistry and Photobiology B: Biology, 1995Lysine was covalently conjugated to calf thymus DNA by irradiation with UV light (wavelength, 253.7 nm). The results showed monofunctional covalent photobinding of lysine molecules with bases in DNA. Only the epsilon-amino group of lysine participated in the photoconjugation reaction. Thymine and cytosine were modified by 60% and 25% respectively.
Najmul Islam, Rashid Ali
openaire +2 more sources
Hydroxymethyl lysine is a source of bioavailable lysine for ruminants1
Journal of Animal Science, 2012Experiments were conducted to evaluate the availability to ruminants of lysine from hydroxymethyl lysine, a product potentially resistant to ruminal degradation yet able to release free lysine when subjected to the acidic environment of the abomasum.
E.A. Elwakeel+5 more
openaire +2 more sources
Advanced Delivery Systems Based on Lysine or Lysine Polymers
Molecular Pharmaceutics, 2021Polylysine and materials that integrate lysine form promising drug delivery platforms. As a cationic macromolecule, a polylysine polymer electrostatically interacts with cells and is efficiently internalized, thereby enabling intracellular delivery. Although polylysine is intrinsically pH-responsive, the conjugation with different functional groups ...
Saeed Manouchehri+3 more
openaire +3 more sources