Results 41 to 50 of about 5,917,729 (124)

Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy [PDF]

open access: yes, 2007
Maternal endothelial dysfunction in preeclampsia is associated with increased soluble fms-like tyrosine kinase-1 (sFlt-1), a circulating antagonist of vascular endothelial growth factor and placental growth factor.
Kellems, Rodney E.   +19 more
core   +1 more source

Genetic and functional traits limit the success of colonisation by arbuscular mycorrhizal fungi in a tomato wild relative

open access: yesPlant, Cell &Environment, Volume 47, Issue 11, Page 4275-4292, November 2024.
Abstract To understand whether domestication had an impact on susceptibility and responsiveness to arbuscular mycorrhizal fungi (AMF) in tomato (Solanum lycopersicum), we investigated two tomato cultivars (“M82” and “Moneymaker”) and a panel of wild relatives including S. neorickii, S. habrochaites and S.
Matteo Chialva   +5 more
wiley   +1 more source

G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton [PDF]

open access: yes, 2005
G protein-coupled receptor kinase 2 (GRK2) phosphorylates and desensitizes activated G protein-coupled receptors (GPCRs). Here, we identify ezrin as a novel non-GPCR substrate of GRK2. GRK2 phosphorylates glutathione S-transferase (GST)-ezrin, but not an
Pitcher, JA, Cant, SH
core  

LORE receptor homomerization is required for 3‐hydroxydecanoic acid‐induced immune signaling and determines the natural variation of immunosensitivity within the Arabidopsis genus

open access: yesNew Phytologist, Volume 242, Issue 5, Page 2163-2179, June 2024.
Summary The S‐domain‐type receptor‐like kinase (SD‐RLK) LIPOOLIGOSACCHARIDE‐SPECIFIC REDUCED ELICITATION (LORE) from Arabidopsis thaliana is a pattern recognition receptor that senses medium‐chain 3‐hydroxy fatty acids, such as 3‐hydroxydecanoic acid (3‐OH‐C10:0), to activate pattern‐triggered immunity.
Sabine Eschrig   +6 more
wiley   +1 more source

EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells [PDF]

open access: yes, 2009
The EGF-related protein EFEMP1 (EGF-containing fibulin-like extracellular matrix protein 1) has been shown to promote tumor growth in human adenocarcinoma.
Jauch, Karl-Walter   +8 more
core   +1 more source

Ligand induced cleavage and nuclear localization of the rice XA21 immune receptor [PDF]

open access: yes, 2012
The rice XA21 receptor confers immunity to the Gram-negative bacterial pathogen, _Xanthomonas oryzae_ pv. _oryzae_ (_Xoo_) upon recognition of the conserved microbial signature AxY^S^22.
Chang-Jin Park, Pamela C. Ronald
core  

GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines [PDF]

open access: yes, 2011
Breakthrough Breast CancerBackground: Gonadotrophin releasing hormone (GnRH) analogs lower estrogen levels in pre-menopausal breast cancer patients. GnRH receptor (GnRH-R) activation also directly inhibits the growth of certain cells.
Sims Andrew H   +27 more
core   +2 more sources

Receptor for activated C kinase-1 facilitates protein kinase C-dependent phosphorylation and functional modulation of GABA(A) receptors with the activation of G-protein-coupled receptors [PDF]

open access: yes, 2002
GABA(A) receptors are the principal sites of fast synaptic inhibition in the brain. These receptors are hetero-pentamers that can be assembled from a number of subunit classes: alpha(1-6), beta(1-3), gamma(1-3), delta(1), epsilon, theta, and pi, but the ...
Trevor G Smart   +7 more
core  

Characterization of a novel bacterial PAMP - elongation factor Tu - and its role in "Arabidopsis thaliana" defense and immunity [PDF]

open access: yes, 2005
The discrimination of self and nonself is a primary challenge for all living organisms to detect microbial invasion and to protect and defend against the invader.
Kunze, Gernot Ulrich
core   +1 more source

Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts [PDF]

open access: yes, 2004
The endothelins are a family of endothelium-derived peptides that possess a variety of functions, including vasoconstriction. Endothelin-1 (ET-1) is up-regulated during tissue repair and promotes myofibroblast contraction and migration, hence ...
Abraham, DJ   +34 more
core   +1 more source

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