Results 111 to 120 of about 11,571 (196)

Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages

, 2021
Jaimy Joy
openalex   +2 more sources

Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Encapsulins are self‐assembling bacterial protein compartments loaded with cargo enzymes. The most abundant encapsulin cargo class are Dye‐decolorizing Peroxidases (DyPs). In this study, we structurally and biochemically characterize a DyP encapsulin found in many enterobacteria.
Natalia C. Ubilla‐Rodriguez, Michael P. Andreas, Tobias W. Giessen   +2 more
wiley   +1 more source

Molecular and biochemical analysis of the system regulating the lytic/lysogenic cycle in the pneumococcal temperate phage MM1 [PDF]

, 2003
Virginia Obregà n, Pedro Garcı́a, Rubens Là pez, José Luis Garcı́a   +3 more
openalex   +1 more source

Nanoneedle‐Based Electroporation for Efficient Manufacturing of Human Primary Chimeric Antigen Receptor Regulatory T‐Cells

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Low reproducibility and inefficient gene transfer hamper clinical manufacturing of chimeric antigen receptor regulatory T cells (CAR Tregs). Nanoneedle mediated electroporation generates primary human CAR Tregs under good manufacturing practice conditions with superior efficiency compared to viral transduction.
Ningjia Sun, Cong Wang, William Edwards, Yikai Wang, Xiangrong L. Lu, Chenlei Gu, Samuel McLennan, Panicos Shangaris, Peng Qi, Daniela Mastronicola, Cristiano Scottà, Giovanna Lombardi, Ciro Chiappini   +12 more
wiley   +1 more source

Functional Silver‐Loaded Porous Composite Scaffold for Bone Tissue Bacterial Infection

Advanced NanoBiomed Research, Volume 5, Issue 6, June 2025.
In the current study, a AgNP‐loaded gelatin/β‐tricalcium phosphate composite scaffold was developed. Its interconnected porous structure facilitated cell adhesion and proliferation while enhancing osteogenic differentiation‐related gene expression to support bone regeneration.
An'nan Hu, Jian Zhou
wiley   +1 more source

Incomplete lytic cycle of a widespread Bacteroides bacteriophage leads to the formation of defective viral particles.

PLoS Biology
Advances in metagenomics have led to the identification of new intestinal temperate bacteriophages. However, their experimental characterization remains challenging due to a limited understanding of their lysogenic-lytic cycle and the common lack of ...
Sol Vendrell-Fernández, Beatriz Beamud, Yasmina Abou Haydar, Jorge Am de Sousa, Julien Burlaud-Gaillard, Etienne Kornobis, Bertrand Raynal, Joelle Vinh, David Bikard, Jean-Marc Ghigo   +9 more
doaj   +1 more source

Modulation ofLactobacillus caseibacteriophage A2 lytic/lysogenic cycles by binding of Gp25 to the early lytic mRNA [PDF]

, 2015
Begoña Carrasco, Susana Escobedo, Juan C. Alonso, Juan E. Suárez   +3 more
openalex   +1 more source

Simultaneous Repression of GLUCAN WATER DIKINASE 1 and STARCH BRANCHING ENZYME 1 in Potato Tubers Leads to Starch With Increased Amylose and Novel Industrial Properties

Biotechnology Journal, Volume 20, Issue 6, June 2025.
Graphical Abstract and Lay Summary Post‐transcriptional gene silencing was used to manufacture potato plants repressed in glucan water dikinase 1 and/or starch branching enzyme 1. This led to an altered starch structure, which affected its physical properties, meaning that the starch can be used in novel industrial processes.
Muyiwa S. Adegbaju, Nina Gouws, Christell van der Vyver, Pedri Claassens, Jens Kossmann, Michaela Fischer‐Stettler, Samuel C. Zeeman, James R. Lloyd   +7 more
wiley   +1 more source

Sigma Factors as Potential Targets to Enhance Recombinant Protein Expression

Biotechnology and Bioengineering, Volume 122, Issue 6, Page 1598-1607, June 2025.
ABSTRACT The transcriptional factors control the expression of many genes and represent an important layer of complexity in cell factories. However, the effect of individual sigma factor deletions from a biomanufacturing perspective has not been addressed. In this contribution, growth, green fluorescence protein (GFP) expression, and oxygen consumption
Laura Pohlen, Emily García, Luz María Martínez, Noemí Flores, Jochen Büchs, Guillermo Gosset, Alvaro R. Lara   +6 more
wiley   +1 more source

Characterization of ES10 lytic bacteriophage isolated from hospital waste against multidrug-resistant uropathogenic E. coli

Frontiers in Microbiology
Escherichia coli is the major causative agent of urinary tract infections worldwide and the emergence of multi-drug resistant determinants among clinical isolates necessitates the development of novel therapeutic agents.
Aneela Nawaz, Sabeena Zafar, Abdulrahman H. Alessa, Nauman Ahmed Khalid, Muqaddas Shahzadi, Alina Majid, Malik Badshah, Aamer Ali Shah, Samiullah Khan   +8 more
doaj   +1 more source