Results 181 to 190 of about 47,686 (230)

Lysophosphatidic Acid Receptors

Molecular Pharmacology, 2000
Lysophosphatidic acid (LPA) is a simple bioactive phospholipid with diverse physiological actions on many cell types. LPA induces proliferative and/or morphological effects and has been proposed to be involved in biologically important processes including neurogenesis, myelination, angiogenesis, wound healing, and cancer progression.
J J, Contos, I, Ishii, J, Chun
openaire   +2 more sources

Lysophosphatidic acid: mitogen and motility factor

Biochemical Society Transactions, 2003
LPA (lysophosphatidic acid), the simplest of al glycerophospholipids, is a potent inducer of cell proliferation, migration and survival. It does so by activating its cognate G-protein-coupled receptors, four of which have been identified. LPA receptors couple to at least three distinct G-proteins and thereby activate multiple signal transduction ...
Leeuwen, F.N. van, Giepmans, B.N., Meeteren, L.A. van, Moolenaar, W.H.   +3 more
openaire   +3 more sources

Lysophosphatidic acid signalling

Current Opinion in Cell Biology, 1995
Lysophosphatidic acid is an intercellular phospholipid messenger that is released from platelets (and probably other cells) and evokes multiple biological responses, ranging from induction of mitogenesis to neurite retraction, by activating a specific G protein coupled receptor.
openaire   +2 more sources

Lysophosphatidic acid in neural signaling

NeuroReport, 2002
The physiological and pathological importance of lysophosphatidic acid (LPA) in the nervous system is underscored by its presence, as well as the expression of its receptors in neural tissues. In fact, LPA produces responses in a broad range of cell types related to the function of the nervous system.
Xiaoqin, Ye, Nobuyuki, Fukushima, Marcy A, Kingsbury, Jerold, Chun   +3 more
openaire   +2 more sources

Lysophosphatidic Acid and Invasion

2009
Lysophosphatidic acid (LPA) is a small, bioactive phospholipid produced by activated platelets, mesothelial cells, macrophage, endothelial cells, fibroblasts, adipocytes, and some cancer cells. It is involved in multiple cellular events of almost every mammalian cell type.
Fengqiang, Wang, David A, Fishman
openaire   +2 more sources