Results 291 to 300 of about 174,460 (337)

π‐Bridged Dimer Strategy of Aggregation‐Induced Emission Molecules to Achieve Very Strong Absorption Ability

Aggregate, EarlyView.
An efficient design strategy is proposed to significantly improve the absorption abilities of AIE molecules. The obtained new AIE molecules indeed exhibit very strong absorption ability. Their molar absorption coefficients up to 95,400 M−1 cm−1 represent one of the state‐of‐the‐art results among the reported AIE molecules.
Liwei Dou, Huanlong Zheng, Haonan Xiong, Shengjie Fu, Chenguang Wang, Di Li   +5 more
wiley   +1 more source

Cross‐Linked Protein Crystals With an Intense Nonconventional Full‐Color Photoluminescence Originating From Through‐Space Intermolecular Interaction

Aggregate, EarlyView.
Cross‐linked protein crystals are introduced as a novel class of nontraditional luminescent materials (NLMs) exhibiting tunable full‐color photoluminescence. Three polymorphic lysozyme crystals establish a clear, definitive structure–emission relationship, revealing that emission originates from intermolecular through‐space interactions (TSI).
Renbin Zhou, Xiaoli Lu, Xuefeng Zhou, Xuejiao Liu, Shanmin Wang, Tymish Y. Ohulchanskyy, Da‐Chuan Yin, Junle Qu   +7 more
wiley   +1 more source

DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v-ATPase Signaling Pathway. [PDF]

CNS Neurosci Ther
Wu Y, Liu X, Luo G, Li Q, Guo B, Li L, Nie J.   +6 more
europepmc   +1 more source

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Chronic lysosome damage boosts interferon responses to Palbociclib through a mitochondrial signalling axis

Bozic M, Lim TE, Kemp AJ, Winnington-Ingram K, Murphy L, Dhir A, Wheeler A, Jimenez-Moreno N, Wilkinson S.   +8 more
europepmc   +1 more source

ZKSCAN3 affects the autophagy‑lysosome pathway through TFEB in Parkinson's disease. [PDF]

Biomed Rep
Yang M, Lin S, Sun B, Chen W, Liu J, Chen M.   +5 more
europepmc   +1 more source

The spectrum of lysosomal stress and damage responses: from mechanosensing to inflammation. [PDF]

EMBO Rep
Scott O, Saran E, Freeman SA.
europepmc   +1 more source