Results 321 to 330 of about 174,460 (337)
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Nature, 1966
IN recent years there has been much interest in the role of crystals in causing acute attacks of gout. Faires and his colleagues at Philadelphia1 and Seegmiller et al. at Bethesda2 were able to produce such attacks by injecting microcrystalline sodium monourate into gouty and non-gouty volunteers.
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IN recent years there has been much interest in the role of crystals in causing acute attacks of gout. Faires and his colleagues at Philadelphia1 and Seegmiller et al. at Bethesda2 were able to produce such attacks by injecting microcrystalline sodium monourate into gouty and non-gouty volunteers.
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Paediatrics and Child Health, 2002
Although most lysosomal storage disorders present in infancy or early childhood with a progressive condition often associated with dysmorphism, considerable genetic heterogeneity exists resulting in a range of illnesses that can include a dramatic neonatal presentation.
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Although most lysosomal storage disorders present in infancy or early childhood with a progressive condition often associated with dysmorphism, considerable genetic heterogeneity exists resulting in a range of illnesses that can include a dramatic neonatal presentation.
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Acta Histochemica, 1987
A characteristic of lysosomal cysteine proteinases is given by their kinetic constants with specific substrates, their sequence homology, and their reactivity with monospecific polyclonal antibodies.
H, Kirschke, B, Wiederanders
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A characteristic of lysosomal cysteine proteinases is given by their kinetic constants with specific substrates, their sequence homology, and their reactivity with monospecific polyclonal antibodies.
H, Kirschke, B, Wiederanders
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1967
Publisher Summary This chapter focuses on the histochemistry of lysosomes. Lysosomes are defined originally as a biochemical entity. Consequently, the biochemical criteria form a basis for the histochemical identification of these particles. Ideally, the prime criteria which appear necessary for the demonstration of a lysosome are (1) the presence of
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Publisher Summary This chapter focuses on the histochemistry of lysosomes. Lysosomes are defined originally as a biochemical entity. Consequently, the biochemical criteria form a basis for the histochemical identification of these particles. Ideally, the prime criteria which appear necessary for the demonstration of a lysosome are (1) the presence of
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2010
Abstract The lysosome is a ubiquitous, single membrane-bond intracellular organelle which continuously recycles biological macromolecules: it not only breaks down cell components but has a dynamic role in nutrient and energy sensing that, through regulatory signalling, is critical for homeostasis and metabolic economy of the cell.
P.B. Deegan, T.M. Cox
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Abstract The lysosome is a ubiquitous, single membrane-bond intracellular organelle which continuously recycles biological macromolecules: it not only breaks down cell components but has a dynamic role in nutrient and energy sensing that, through regulatory signalling, is critical for homeostasis and metabolic economy of the cell.
P.B. Deegan, T.M. Cox
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2014
Lysosomal storage diseases (LSDs) are a group of more than 50 inherited metabolic disorders that result from defective lysosomal acid hydrolysis of endogenous macromolecules causing their accumulation (Winchester et al 2000). A classification based on the nature of the primary stored material involved is reported in Table 1.
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Lysosomal storage diseases (LSDs) are a group of more than 50 inherited metabolic disorders that result from defective lysosomal acid hydrolysis of endogenous macromolecules causing their accumulation (Winchester et al 2000). A classification based on the nature of the primary stored material involved is reported in Table 1.
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, 2005 1979
Steroids in general and glucocorticoids in particular affect lysosomes in various ways. The explanation of these effects remains in dispute, however. Theories include the view that steroids interact directly with lysosomal membranes, that steroids provoke induced changes in lysosomes, and that classical steroid receptors originate in lysosomes ...
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Steroids in general and glucocorticoids in particular affect lysosomes in various ways. The explanation of these effects remains in dispute, however. Theories include the view that steroids interact directly with lysosomal membranes, that steroids provoke induced changes in lysosomes, and that classical steroid receptors originate in lysosomes ...
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