Dual Combined Real-Time Reverse Transcription Polymerase Chain Reaction Assay for the Diagnosis of Lyssavirus Infection. [PDF]
PLoS Neglected Tropical Diseases, 2016 The definitive diagnosis of lyssavirus infection (including rabies) in animals and humans is based on laboratory confirmation. The reference techniques for post-mortem rabies diagnosis are still based on direct immunofluorescence and virus isolation, but
Laurent Dacheux +8 more
doaj +1 more source
Bat and pig IFN-induced transmembrane protein 3 restrict cell entry by influenza virus and lyssaviruses [PDF]
, 2015 IFN-induced transmembrane protein 3 (IFITM3) is a restriction factor that blocks cytosolic entry of numerous viruses that utilize acidic endosomal entry pathways. In humans and mice, IFITM3 limits influenza-induced morbidity and mortality.
Benfield, C. +13 more
core +4 more sources
Modern building structures are a landscape‐level driver of bat–human exposure risk in Kenya
Frontiers in Ecology and the Environment, Volume 23, Issue 1, February 2025.Identifying the locations and drivers of high‐risk interfaces between humans and wildlife is crucial for managing zoonotic disease risk. We suggest that continent‐wide improvements to residential housing in Africa are inadvertently creating artificial roosting habitat for synanthropic free‐tailed bats (family Molossidae), and that improved buildings ...
Tamika J Lunn +4 more
wiley +1 more source
Intergenotypic Replacement of Lyssavirus Matrix Proteins Demonstrates the Role of Lyssavirus M Proteins in Intracellular Virus Accumulation [PDF]
Journal of Virology, 2010 ABSTRACT Lyssavirus assembly depends on the matrix protein (M). We compared lyssavirus M proteins from different genotypes for their ability to support assembly and egress of genotype 1 rabies virus (RABV). Transcomplementation of M-deficient RABV with M from European bat lyssavirus (EBLV) types 1 and 2 reduced the release of infectious virus.
Stefan Finke +4 more
openaire +3 more sources
Raccoon density estimation from camera traps for raccoon rabies management
The Journal of Wildlife Management, Volume 89, Issue 2, February 2025.We examined if we could reliably estimate densities of unmarked raccoons from camera trap images by comparing against densities from concurrent live‐trapping mark recapture studies. Our results show promise that cameras can be used to assign densities to raccoon density index bins that are used for raccoon rabies management.
Amy J. Davis +7 more
wiley +1 more source
Temporal dynamics of European bat Lyssavirus type 1 and survival of Myotis myotis bats in natural colonies. [PDF]
PLoS ONE, 2007 Many emerging RNA viruses of public health concern have recently been detected in bats. However, the dynamics of these viruses in natural bat colonies is presently unknown.
Blanca Amengual +3 more
doaj +1 more source
Neglected Tropical Diseases and Female Infertility: Possible Pathophysiological Mechanisms
Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.Battling female infertility has posed a global challenge, where neglected tropical diseases (NTDs) are nonetheless a notable contributing factor. NTDs affect a variety of diseases, often of a chronic nature, which are often cited as some of the most lethal diseases operating against the most economically disadvantaged populations across the globe.
Moses Agbomhere Hamed +8 more
wiley +1 more source
Development of broad-spectrum human monoclonal antibodies for rabies post-exposure prophylaxis [PDF]
, 2016 Currently available rabies post-exposure prophylaxis (PEP) for use in humans includes equine or human rabies immunoglobulins (RIG). The replacement of RIG with an equally or more potent and safer product is strongly encouraged due to the high costs and ...
Agatic, G. +41 more
core +4 more sources
Chimeric Lyssavirus Glycoproteins with Increased Immunological Potential [PDF]
Journal of Virology, 1999 ABSTRACTThe rabies virus glycoprotein molecule (G) can be divided into two parts separated by a flexible hinge: the NH2half (site II part) containing antigenic site II up to the linear region (amino acids [aa] 253 to 275 encompassing epitope VI [aa 264]) and the COOH half (site III part) containing antigenic site III and the transmembrane and ...
Jallet, Corinne +6 more
openaire +4 more sources
Australian Bat Lyssavirus Infection in a Captive Juvenile Black Flying Fox
Emerging Infectious Diseases, 1999 The newly emerging Australian bat lyssavirus causes rabieslike disease in bats and humans. A captive juvenile black flying fox exhibited progressive neurologic signs, including sudden aggression, vocalization, dysphagia, and paresis over 9 days and then ...
Hume E. Field +2 more
doaj +1 more source