Results 51 to 60 of about 120,236 (192)

Molecular mechanism of lytic polysaccharide monooxygenases

Chemical Science, 2018
The lytic polysaccharide monooxygenases (LPMOs) are copper metalloenzymes that can enhance polysaccharide depolymerization through an oxidative mechanism and hence boost generation of biofuel from e.g. cellulose. By employing density functional theory in a combination of quantum mechanics and
Erik Donovan Hedegård, Ulf Ryde
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Structural diversity of lytic polysaccharide monooxygenases

Current Opinion in Structural Biology, 2017
Lytic polysaccharide monooxygenases (LPMOs) catalyze the oxidative cleavage of glycosidic bonds and represent a promising resource for development of industrial enzyme cocktails for biomass processing. LPMOs show high sequence and modular diversity and are known, so far, to cleave insoluble substrates such as cellulose, chitin and starch, as well as ...
Vaaje-Kolstad, Gustav, Forsberg, Zarah, Loose, Jennifer Sm, Bissaro, Bastien, Eijsink, Vincent Gh   +4 more
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Functional characterization of a lytic polysaccharide monooxygenase from the thermophilic fungus Myceliophthora thermophila. [PDF]

PLoS ONE, 2018
Thermophilic fungi are a promising source of thermostable enzymes able to hydrolytically or oxidatively degrade plant cell wall components. Among these enzymes are lytic polysaccharide monooxygenases (LPMOs), enzymes capable of enhancing biomass ...
Marco A S Kadowaki, Anikó Várnai, John-Kristian Jameson, Ana E T Leite, Antonio J Costa-Filho, Patricia S Kumagai, Rolf A Prade, Igor Polikarpov, Vincent G H Eijsink   +8 more
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Lytic Polysaccharide Monooxygenases as Chitin-Specific Virulence Factors in Crayfish Plague

Biomolecules, 2021
The oomycete pathogen Aphanomyces astaci, also known as “crayfish plague”, is an obligate fungal-like parasite of freshwater crustaceans and is considered responsible for the ongoing decline of native European crayfish populations. A.
Federico Sabbadin, Bernard Henrissat, Neil C. Bruce, Simon J. McQueen-Mason   +3 more
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of Lytic polysaccharide monooxygenases from Myceliophthora thermophila C1 differ in substrate preference and reducing agent specificity

, 2016
of Lytic polysaccharide monooxygenases from Myceliophthora thermophila C1 differ in substrate preference and reducing agent ...
Adrie Westphal (3451130), Matthias Frommhagen (3451121), Mirjam Kabel (3451115), Martijn Koetsier (3451112), Willem Berkel (3507473), Sandra Hinz (3451124), Jean-Paul Vincken (550043), Harry Gruppen (550039), Jaap Visser (3451127)   +8 more
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AA16, a new lytic polysaccharide monooxygenase family identified in fungal secretomes

Biotechnology for Biofuels, 2019
Background Lignocellulosic biomass is considered as a promising alternative to fossil resources for the production of fuels, materials and chemicals. Efficient enzymatic systems are needed to degrade the plant cell wall and overcome its recalcitrance.
Camille Filiatrault-Chastel, David Navarro, Mireille Haon, Sacha Grisel, Isabelle Herpoël-Gimbert, Didier Chevret, Mathieu Fanuel, Bernard Henrissat, Senta Heiss-Blanquet, Antoine Margeot, Jean-Guy Berrin   +10 more
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Production of functionalised chitins assisted by fungal lytic polysaccharide monooxygenase

, 2018
The gene CCT67099 from Fusarium fujikuroi was shown to encode a novel enzyme from the Lytic Polysaccharide Monooxygenase (LPMO) Family AA11.
Wang, Damao, Vaibhav Srivastava, Hsieh, Yves S. Y., Srivastava, Vaibhav, Bulone, Vincent, Damao Wang, Sellberg, J.A., Wang, Damao,, McKee, Lauren S.,, McKee, Lauren S., Salazar-Alvarez, Germán,, Jing Li, Sellberg, Jonas A.,, Jonas A. Sellberg, Bulone, V., Yves S. Y. Hsieh, Lauren S. McKee, Hsieh, Y.S.Y., Germán Salazar-Alvarez, Bulone, Vincent,, Hsieh, Yves S. Y.,, McKee, L.S., Srivastava, V., Li, Jing, Sellberg, Jonas A., Srivastava, Vaibhav,, Vincent Bulone, Salazar-Alvarez, G., Wang, D., Li, J., Li, Jing,   +30 more
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Production and spectroscopic characterization of lytic polysaccharide monooxygenases [PDF]

, 2018
Lytic polysaccharide monooxygenases (LPMOs, also known as PMOs) are a recently discovered family of enzymes that play a key role in the breakdown of polysaccharide substrates. The ability of LPMOs to introduce chain breaks, using an oxidative mechanism, has particularly attracted attention as the world seeks more cost-effective and environmentally ...
Hemsworth, Glyn R., Ciano, Luisa, Davies, Gideon J., Walton, Paul H.   +3 more
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Neutron and Atomic Resolution X-ray Structures of a Lytic Polysaccharide Monooxygenase Reveal Copper-Mediated Dioxygen Binding and Evidence for N-Terminal Deprotonation [PDF]

, 2017
A 1.1 Å resolution, room-temperature X-ray structure and a 2.1 Å resolution neutron structure of a chitin-degrading lytic polysaccharide monooxygenase domain from the bacterium Jonesia denitrificans (JdLPMO10A) show a putative dioxygen species ...
John-Paul Bacik, Mekasha, Sophanit, Zarah Forsberg, Vincent G. H. Eijsink, Julian C.-H. Chen, Forsberg, Zarah, Jay C. Nix, Andrey Y. Kovalevsky, Coates, Leighton, Matthew J. Cuneo, Gustav Vaaje-Kolstad, Leighton Coates, Bacik, John-Paul, Nix, Jay C, Cuneo, Matthew J, Eijsink, Vincent GH, Chen, Julian C-H, Vaaje-Kolstad, Gustav, Sophanit Mekasha, Clifford J. Unkefer, Kovalevsky, Andrey Y, Unkefer, Clifford J   +21 more
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Hemicellulose content affects the properties of cellulose nanofibrils produced from softwood pulp fibres by LPMO

, 2022
After lytic polysaccharide monooxygenase (LPMO) treatment, colloidally stable and thin cellulose nanofibrils (CNFs) of a uniform width are produced from kraft pulp fibres, which has a higher hemicellulose content than dissolving pulp fibres.
Koskela, Salla,, Zhou, Qi,, Yan, Max,, Li Zha, Shennan Wang, Salla Koskela, Wang, Shennan,, Max Yan, Zha, Li,, Qi Zhou   +9 more
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