Results 11 to 20 of about 2,789 (134)

New Quinoline Kinase Inhibitors With Good Selectivity for NAK Kinases and Anti-Tumor Activity Against Ewing Sarcoma. [PDF]

Arch Pharm (Weinheim)
Focusing on the discovery of new therapeutics for childhood cancer, novel quinoline derivatives were synthesized and demonstrated activity against Ewing sarcoma. A target search was performed against a panel of kinases, and the compounds showed selectivity for the NAK family, mainly GAK, which was confirmed by enzyme kinetic assays.
Gentz CB, Fernandes THM, Lopes MS, Elson L, Krämer A, Souza LR, Fortes IS, Pinto GS, Martins MCS, Lima HB, Santiago ADS, Gregianin LJ, Massirer KB, Bengtson MH, Roesler R, Knapp S, Laufer SA, Andrade SF.   +17 more
europepmc   +2 more sources

Biochemical Responses of Anopheles spp. Larvae to a Novel Brazilian BR101 Bacillus thuringiensis var. israelensis Formulation: Oxidative Stress, Detoxification Enzymes, and Safety for Nontarget Notonectidae and Gerridae Aquatic Insects. [PDF]

Chem Biodivers
Bti BR101 exhibits strong larvicidal activity against Anopheles larvae spp., with dose‐dependent mortality and LC50 of 3.13 µg/mL. Bti increases ROS, lipid and protein oxidation, and activates antioxidant enzymes (SOD, CAT, GPx) and detoxification pathways (MFO and esterases), indicating moderate oxidative stress.
de Oliveira Bentes IC, Abensour DD, Lima da Costa ML, de Moreira Sampaio RT, Bernadete da Silva L, da Silva Ferreira FA, da Silva Tavares CP, Vieira de Souza H, de Assis Marque F, Navarro da Silva MA, de Lima EA, Vilas-Boas GT, Zequi JAC, de Oliveira AC, Roque RA.   +14 more
europepmc   +2 more sources

Regenerative Potential of Mesenchymal Stem Cells for Enhancing Uterine Health and Fertility in Repeat Breeder Dairy Cows [PDF]

Stem Cells Int
The suboptimal reproductive performance of repeat‐breeding (RB) cows is a major challenge for the dairy industry, leading to higher costs, prolonged calving intervals, and reduced productivity, negatively impacting herd productivity and economic viability.
Ribeiro B, Fülber J, Reyes Aleman M, Pfeifer L, de Souza Andrade J, Moreira E, de Silva R, Baccarin R, de Sá L, Li J, Gregory L.   +10 more
europepmc   +2 more sources

O ethos como instância constitutiva da construção da ‘imagem de autor’

Cadernos de Estudos Lingüísticos, 2019
Neste artigo, pretendemos verificar em que medida o ethos discursivo (MAINGUENEAU, 2005, 2008a) afeta a construção da ‘imagem de autor’ (MAINGUENEAU, 2010a, 2010b).
Fernanda Mussalim, Breno Rafael M. P. R. Rezende   +1 more
doaj   +1 more source

Arnauld & Andrade: dos projetores às galerias sem lâmpadas

Outra Travessia, 2016
O texto reflete sobre a condição da fotografia e sua relação com o rosto e o povo, a partir de encadear uma série de reflexões dos escritores Mário de Andrade e Celine Arnaud, e das diferenças entre os dois surgidas em relação à figura de Charlie ...
Raul Antelo
doaj   +1 more source

O JABOTI GRANDE The big tortoise

Signótica, 1998
Este trabalho busca provar a eficiência da equação mencionada por Mário deAndrade em prefácio não publicado de Macunaíma: Clan do jaboti + Amarverbo intransitivo = Macunaíma.This work consists of proving the efficiency of the equation mentioned byMário ...
VIVIANE FLEURY DE FARIA
doaj   +1 more source

Characterization of Transcriptional, Epigenetic, and Phenotypic Plasticity and Discovery of Biomarkers in Acute and Chronic Murine Schistosomiasis Infection [PDF]

FASEB J
Workflow for discovering parasitological and molecular changes related to Schistosoma mansoni infection. ABSTRACT Parasites can induce changes in their hosts, favoring the success of the infection and its development at each stage of their life cycle.
Corrêa S, Oliveira Teodoro C, Luz da Silva J, Queiroz F, do Amaral T, Allegretti S, de Oliveira F, Teixeira R, de Sousa L, Consonni S, Gomes M, Grunau C, Cabral F.   +12 more
europepmc   +2 more sources

Mário de Andrade e Richard Wagner na aurora do modernismo paulista

Estudos Avançados
RESUMO O início da carreira intelectual de Mário de Andrade é marcado por aproximações com o compositor alemão Richard Wagner de diversas maneiras. No presente artigo, apresento três modos pelos quais os autores se encontram: o primeiro é a leitura que ...
EDUARDO TADAFUMI SATO
doaj   +1 more source

Technological Properties of Biocomposites Produced With Agro‐Industrial Castor Waste Applicable in the Thermal Insulation of Buildings

Polymer Composites, EarlyView.
Biocomposites produced with agro‐industrial waste from castor hulls and pinewood bonded with urea‐formaldehyde adhesive, intended for application as thermal insulation in buildings. ABSTRACT The production of composite particleboards with agricultural waste has been the focus of many studies that aim to address environmental problems due to waste ...
Thamirys Andrade Lopes, Douglas Lamounier Faria, Felipe Gomes Batista, Adriele de Lima Felix, Antônio Claret Matos, Mário Vanoli Scatolino, Julio Soriano, Lourival Marin Mendes   +7 more
wiley   +1 more source

A poesia de Manuel Bandeira: a crítica de Mário de Andrade e Sérgio Buarque de Holanda

Estudos Avançados
RESUMO A poesia de Manuel Bandeira, um dos mais profícuos poetas brasileiros do século XX, interessou tanto à crítica literária de Mário de Andrade quanto à de Sérgio Buarque de Holanda.
RICARDO GAIOTTO DE MORAES
doaj   +1 more source