Results 91 to 100 of about 1,125,732 (289)

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source

Sindactilia pós-queimadura da mão

Revista Brasileira de Cirurgia Plástica
INTRODUÇÃO: A sindactilia por queimadura é uma sequela grave e incapacitante, e limita a função preensora da mão. Na maioria dos casos, é decorrente de má orientação cicatricial na fase aguda da queimadura.
Luiz Mário Bonfatti Ribeiro, Vicente Scopel de Morais, Flávio Amoretti Fachinelli   +2 more
doaj   +1 more source

Avaliação Funcional Global da Mão na Criança [PDF]

, 1997
O estudo da criança com patologia da mão levou a autora a criar um teste baseado numa avaliação funcional da mão do adulto, sob a forma de um jogo infantil.
Costa, MJ
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Hyperelastic Starch Hydrogel Configures Edible and Biodegradable All‐Components for Soft Robots

Advanced Science, EarlyView.
Hyperelastic starch hydrogel is tailored via a phase separation strategy of solvent‐antisolvent co‐modulation. The mechanical performance of starch hydrogel is widely tuned with maximum strains: 194.4–361.4%; maximum tensile stresses: 34–192 kPa; and Young's moduli: 36.0–205.8 kPa. Notably, the hydrogel achieves complete soil degradation within 24 days
Siyu Yao, Haohao Hu, Mengfan Zhang, Qingqing Zhu, Donghong Liu, Shaoxing Qu, Guoyong Mao, Enbo Xu   +7 more
wiley   +1 more source

Slavery, Subversion and Subalternity: Gender and Violent Resistance in Nineteenth-Century Bahia [PDF]

, 1999
1999-01 ...

core  

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Social Defeat Stress Decreases mRNA for Monoamine Oxidase A and Increases 5-HT Turnover in the Brain of Male Nile Tilapia (Oreochromis niloticus)

Frontiers in Pharmacology, 2019
Stress induces various neurobiological responses and causes psychiatric disorders, including depression. Monoamine oxidase A (MAO-A) plays an important role in various functions of the brain, such as regulation of mood, anxiety and aggression, and ...
Yuki Higuchi, Tomoko Soga, Ishwar S. Parhar   +2 more
doaj   +1 more source

Tecnologia social: uma estratégia para o desenvolvimento [PDF]

, 2004
Esta publicação apresenta reflexões de diversos representantes de instituições governamentais, do terceiro setor, da sociedade civil e de universidades sobre o tema da Tecnologia ...
Antonio E. Lassance, Jr., Claiton José Mello, Eduardo José Siqueira Barbosa, Flávio Cruvinel Brandão, Henrique Tahan Novaes, Jacqueline Rutkowski, Jacques De Oliveira Pena, Juçara Santiago Pedreira, Ladislau Dowbor, Paul Singer, Renato Dagnino, Sidney Lianza, Silvio Caccia Bava, Sonia Maria Portella Kruppa   +13 more
core  

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Avaliação dos desempenhos econômico e socioambiental de sistemas modais de pecuária de cria com modelos dea com restrições aos pesos. [PDF]

, 2011
Este estudo avaliou o desempenho de 21 sistemas modais de produção de gado de corte que realizam apenas a fase de cria, em municípios de sete estados do Brasil. Foram propostos e aplicados dois modelos DEA BCC segundo enfoques distintos.
ABREU, U. G. P. de, CARVALHO, T. B. de, GOMES, E. G., MELLO, J. C. C. B. S. de, ZEN, S. de   +4 more
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