Results 121 to 130 of about 1,125,732 (289)

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Estimativa de custo de produção e lucratividade da soja, safra 2008/09, para o Paraná e Santa Catarina. [PDF]

, 2011
Custo dos insumos. Custo das máquinas, equipamentos e operações. Custo de mão-de-obra, taxas e benfeitorias. Custos sem considerar o custo de utilização da terra. Preço da saca e número de sacas. Custos considerando o custo de utilização da terra.
HIRAKURI, M. H.
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Magnesium Structure‐Function Integration Platform for Spatiotemporal Multi‐Modality Therapy: Combining Hormonotherapy and Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
The schematic illustration of the MHSCG platform for spatiotemporal responsive GRb1 release to induce androgen deprivation therapy (ADT) and immunogenic cell death (ICD) multimodal therapy in prostate cancer. Abstract Metal‐based immunotherapy represents a promising strategy for enhancing antitumor efficacy; however, its clinical application is limited
Rui Zan, Qianping Mao, Keyi Wang, Guodong Zou, Shi Yang, Hua Qiu, Xiang Fang, Guiqing Wang, Xinyi Zhou, Jiexia Wen, Shuai Jiang, Ran Huang, Qiuming Peng, Tao Suo   +13 more
wiley   +1 more source

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

Advanced Science, EarlyView.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men, Chenchen Wu, Lei Wang, Shengjie Gao, Yu Mao, Wei Liu, Changhong Liu, Lei Zheng   +7 more
wiley   +1 more source

Análise dos custos de colheita do café no sistema safra zero em comparação ao sistema tradicional de derriça no pano. [PDF]

, 2011
A colheita representa 25 a 35% do custo direto da produção do café e utiliza o maior contingente de mão de obra de todo o ciclo da cultura. Por isso, a adoção de estratégias para a colheita do café, como o uso de máquinas de pequeno e grande porte ...
ALMEIDA, G. R. R., BARROS, U. V., CARVALHO, C. H. S. de, MENDONÇA, J. M. A., SILVEIRA, J. S. M.   +4 more
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Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Coumarin derivatives as inhibitors against monoamine oxidase: structure-activity relationships and inhibitory mechanisms

Acta Materia Medica
Monoamine oxidase (MAO) is a useful target in the treatment of neurodegenerative diseases and depressive disorders. Understanding the structure-activity relationship (SAR) and mechanisms underlying MAO inhibitors is crucial but challenging.
Jie Sun, Leizhi Xu, Qiusha Pan, Pu Wang, Qingguang Zhang, Ping Wang, Yangliu Xia   +6 more
doaj   +1 more source

A safra do imbuzeiro em comunidades de pequenos agricultores da região semi-árida da Bahia. [PDF]

, 2016
Entre as fruteiras nativas que ocorrem na região semi-árida do Nordeste, o imbuzeiro tem contribudo substancialmente para a sobrevivencia dos pequenos agricultores e animais da região, principalmente os silvestres.
CAVALCANTI, N. de B., RESENDE, G. M. de
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DNMT2‐m5C‐ACLY Axis Promotes Lenvatinib Resistance in Hepatocellular Carcinoma Through Histone Acetylation‐Mediated Notch Pathway

Advanced Science, EarlyView.
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang, Jie Li, Shengwei Mao, Xuhui Zhao, Douwaner Liu, Jiafeng Chen, Jialu Fu, Yichao Bu, Xiaoling Wu, Shaoqing Liu, Qifeng Yu, Qiongzhu Dong, Zheng Tang, Yuan Fang, Yinghong Shi   +14 more
wiley   +1 more source

Caracterização biomecânica do gesto de alcançar em individuos pós Acidente Vascular Encefálico [PDF]

, 2012
É objectivo deste trabalho caracterizar biomecanicamente o gesto de alcançar em indivíduos pós Acidente Vascular Encefálico. A amostra é constituída por 4 indivíduos sem patologia do foro neuro-músculo-esquelético e 4 indivíduos com confirmação ...
Correia, Miguel V., Santos, Rubim, Silva, Cláudia C., Vilas Boas, João   +3 more
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