Results 131 to 140 of about 1,125,732 (289)

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

O Auto da Compadecida - A Dog's Will: an analysis of the translation of idioms in the English subtitle [PDF]

, 2014
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro de Comunicação e Expressão. Letras Inglês.The objective of this study is to analyse the English subtitles of the Brazilian film O Auto da Compadecida – A Dog’s Will (Arraes, 2000) – in ...
Lubianco de Sá, Emilene
core  

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Manejo correto da ordenha e qualidade do leite. [PDF]

, 2012
Muitas vezes o produtor se questiona quais as vantagens de adotar duas ou três ordenhas diárias. A resposta para esta pergunta tem que considerar uma série de fatores, tais como o custo da mão de obra, custos adicionais conseqüentes da realização de uma ...
PORTELLA, J. da S., SUÑÉ, R. W., VERAS, M. M.   +2 more
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A Modular DNAzyme for Precise Visualization and Intervention of Alternative Splicing Isoforms in Live Cells

Advanced Science, EarlyView.
A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin, Jiale Sun, Yuqing Mao, Yuhao Tang, Fuan Wang, Zhihong Liu, Jing Wang   +6 more
wiley   +1 more source

In vitro comparative study of composite coatings for magnesium-based bone implants

Results in Surfaces and Interfaces
This study provides a comparative assessment of the corrosion, morphology, and biological properties of four of the most promising coating methods for magnesium in biomedical applications, namely micro-arc oxidation (MAO), graphene oxide (GO)-containing ...
Abdelrahman Amin, Bryce Williams, Thomas McGehee, Alyssandra Navarro, Vipul Patil, Mostafa Elsaadany, Hamdy Ibrahim   +6 more
doaj   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

Caracterização da agroindústria do leite na região oeste do estado do Pará. [PDF]

, 2015
O trabalho caracterizou a situação do setor agroindustrial ligado ao processamento de leite na região oeste do estado do Pará. A pesquisa abrangeu cinco laticínios localizados nos municípios de Itaituba, Rurópolis, Trairão e Placas.
SANTOS, J. C. dos, SANTOS, M. A. S. dos, SENA, A. L. dos S.   +2 more
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Enhanced Oxygen Redox Activity and Structure Stability of P2‐Type Manganese‐Based Cathodes Through Medium‐Entropy Strategy

Advanced Science, EarlyView.
A medium‐entropy strategy guided by ionic potential is applied to weaken TM─O bonds and suppress Jahn–Teller distortion in P2‐type cathodes, thereby enhancing the oxygen redox activity and structure stability. A medium‐entropy oxide, Na0.8Li0.1Ni0.1Cu0.1Ti0.1Mn0.6O2, demonstrates a high reversible capacity of 223.7 mAh g−1 and an energy density of 616 ...
Dongxiao Wang, Yuxuan Liu, Zihao Wang, Wei Su, Xingguo Qi, Huican Mao, Kan Zhang, Shigang Lu, Bingkun Guo, Yingchun Lyu   +9 more
wiley   +1 more source

Rua de mão dupla:

Artefilosofia, 2017
Reclame, publicidade, propaganda. A despeito das nuances semânticas, todos esses termos aparecem nos escritos de Walter Benjamin para iluminar a via de mão dupla aberta entre a arte e a técnica, notadamente a partir de meados do século XIX.
Aléxia Bretas
doaj