Results 11 to 20 of about 1,125,732 (289)
Molecules, 2014 Propolis is the resinous material that bees gather from leaf buds, flowers and vegetables. Propolis extracts contain constituents with a broad spectra of pharmacological properties and are important ingredients of popular dietary supplements.
Narayan D. Chaurasiya +4 more
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A critical appraisal of MAO-B inhibitors in the treatment of Parkinson’s disease
Journal of neural transmission, 2022 Since the 1980s, the MAO-B inhibitors have gained considerable status in the therapy of the Parkinson’s disease. In addition to the symptomatic effect in mono- and combination therapies, a neuroprotective effect has repeatedly been a matter of some ...
W. Jost
semanticscholar +1 more source
Redefining differential roles of MAO-A in dopamine degradation and MAO-B in tonic GABA synthesis
Experimental and Molecular Medicine, 2021 Monoamine oxidase (MAO) is believed to mediate the degradation of monoamine neurotransmitters, including dopamine, in the brain. Between the two types of MAO, MAO-B has been believed to be involved in dopamine degradation, which supports the idea that ...
Hyun-U Cho +7 more
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Monoamine Oxidase (MAO) as a Potential Target for Anticancer Drug Design and Development
Molecules, 2021 Monoamine oxidases (MAOs) are oxidative enzymes that catalyze the conversion of biogenic amines into their corresponding aldehydes and ketones through oxidative deamination.
Reem Aljanabi +5 more
semanticscholar +1 more source
Nature Communications, 2020 The antiandrogen enzalutamide (Enz) has improved survival in castration resistant prostate cancer (CRPC) patients. However, most patients eventually develop Enz resistance that may involve inducing the androgen receptor (AR) splicing variant 7 (ARv7 ...
Ke-liang Wang +14 more
semanticscholar +1 more source
Science Advances, 2019 KDS2010, a MAO-B inhibitor, shows a long-lasting effect in alleviating memory impairment in an Alzheimer’s disease mouse model. Monoamine oxidase–B (MAO-B) has recently emerged as a potential therapeutic target for Alzheimer’s disease (AD) because of its
Jong-Hyun Park +27 more
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Disease Models & Mechanisms, 2022 Monoamine oxidase (MAO) deficiency and imbalanced levels of brain monoamines have been associated with developmental delay, neuropsychiatric disorders and aggressive behavior.
Diego Baronio +2 more
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Inhibitors of MAO-A and MAO-B in Psychiatry and Neurology
Frontiers in Pharmacology, 2016 Inhibitors of MAO-A and MAO-B are in clinical use for the treatment of psychiatric and neurological disorders respectively. Elucidation of the molecular structure of the active sites of the enzymes has enabled a precise determination of the way in which ...
J. Finberg, J. Rabey
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Lipomas Gigantes da Eminência Tenar
Revista Iberoamericana de Cirugía de la Mano, 2013 Resumo Os autores apresentam 4 casos de lipomas gigantes da eminência tenar. Os lipomas correspondem apenas a cerca de 5% dos tumores da mão. São escassos os casos na literatura de lipomas gigantes nesta localização.
J. Fraga Ferreira +2 more
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Revista Brasileira de Reumatologia, 2004 OBJECTIVE: To evaluate the use of a static positioning orthesis for boutonnière deformity on the thumb. METHODS: Twenty women aged between 25 and 74 years old were included in the study.
Silmara Nicolau Pedro da Silva +4 more
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