Results 151 to 160 of about 567,812 (303)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Référenceur et référencement. Cachez ces pratiques que je ne saurais voir
Sur le Journalisme, 2014 A partir d’entretiens réalisés chez des éditeurs de presse en ligne français, nous dressons le portrait de plusieurs employés en charge d’optimiser le référencement des documents produits par les journalistes sur les moteurs de recherche, et en ...
Guillaume Sire
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Environment, international cooperation and climate change
Meridiano 47, 2017 Russian behavior within the Climate Change International Regime is an interesting case for comprehending this normative framework possibilities and challenges in contemporary international stage.
Daniela Vieira Secches +1 more
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Economia terciária nas cidades médias do estado do Ceará, Brasil: evolução e concentração [PDF]
, 2020 Walas Wedel Martins de Santana +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Le temps des plateformes : enjeux, différences et complémentarité de l’archivage des médias sociaux numériques à la Bibliothèque nationale de France et à l’Institut national de l’audiovisuel [PDF]
Alexandre Fay +2 more
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
MÉTODO AHP/PROMETHEE NA AVALIAÇÃO DA SUSTENTABILIDADE DE FORNECEDORES DE PEQUENAS E MÉDIAS EMPRESAS [PDF]
Gabriel Brito Caldas +2 more
openalex +1 more source