Results 221 to 230 of about 568,996 (254)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Prevalence of depression and analysis of its association with anxiety in military police officers: a cross-sectional study. [PDF]

Rev Bras Enferm
Silva RCDD, Mendes CV, Fernandes MNF, Silva GG, Vilela LBF, Camargo Júnior EB.   +5 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Time series analysis (2015-2022): dengue risk scenario in Goiás, Brazil. [PDF]

Rev Bras Epidemiol
Oliveira Junior RR, Modesto ACF, Assunção LDP, Pena LJ, Feres VCR.   +4 more
europepmc   +1 more source

The Somalia Affair The Oxford Companion to Canadian Military History [PDF]

, 2015
Dean F. Oliver, J.L. Granatstein
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Mapping the political landscape from data traces: Multidimensional opinions of users, politicians and media outlets on X. [PDF]

Data Brief
Vendeville A, Royo-Letelier J, Cassells D, Cointet JP, Crépel M, Faverjon T, Lenoir T, Mazoyer B, Ooghe-Tabanou B, Pournaki A, Yamashita H, Ramaciotti P.   +11 more
europepmc   +1 more source

The depiction of the worst thing: on the meaning and use of images of the terrible [PDF]

, 2013
Verschaffel, Bart
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Basal activation of astrocytic Nrf2 in neuronal culture media: Challenges and implications for neuron-astrocyte modelling. [PDF]

Brain Neurosci Adv
Elsharkasi MMO, Villani B, Wells G, Kerr F.   +3 more
europepmc   +1 more source