Results 1 to 10 of about 1,096 (49)

Réduction de l’utilisation des antibiotiques en filières animales : Quelles mesures, quels résultats, quelles perspectives ?

open access: yesINRAE Productions Animales, 2023
Promouvoir un usage responsable et prudent des antibiotiques est un axe clé des plans d’action internationaux, européens et nationaux pour lutter contre l’antibiorésistance.
Delphine URBAN   +5 more
doaj   +1 more source

Prevention and management of health products shortages by the French national agency (ANSM), 10 years of experience

open access: yesFrontiers in Public Health, 2023
Shortages of drugs and medical devices have tended to increase in France and worldwide, with consequences for patients and healthcare professionals. Preventing shortages of health products has become a priority for regulatory authorities, including the ...
Laëtitia Belgodère   +25 more
doaj   +1 more source

Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model

open access: yesMolecules, 2021
Mitogen- and Stress-Activated Kinase 1 (MSK1) is a nuclear kinase, taking part in the activation pathway of the pro-inflammatory transcription factor NF-kB and is demonstrating a therapeutic target potential in inflammatory diseases such as asthma ...
Maud Bollenbach   +11 more
doaj   +1 more source

Conceptual Framework of the Design of Pleiotropic Drugs against Alzheimer’s Disease

open access: yesPharmaceutics, 2023
The multifactorial nature of some diseases, particularly neurodegenerative diseases such as Alzheimer’s disease, frequently requires the use of several drugs. These drug cocktails are not without drawbacks in terms of increased adverse effects, drug–drug
Thomas Guiselin   +3 more
doaj   +1 more source

Investigating the efficacy and safety of metronidazole during pregnancy; A systematic review and meta-analysis

open access: yesEuropean Journal of Obstetrics & Gynecology and Reproductive Biology: X, 2021
Objective: We aimed to review and analyze studies focusing on the efficacy of metronidazole in reducing the risk of preterm birth and the safety of metronidazole taking into account the different doses, duration of treatment and routes of administration.
Priscilla Ajiji   +5 more
doaj   +1 more source

Séparer l’aliment du médicament

open access: yesSocio-anthropologie, 2021
Since the beginning of the 1990s, Europe has seen an increase in the number of boundary products that explicitly place themselves between the drug whose "health benefits" they claim and the food to which they are legally bound.
Solenne Carof, Étienne Nouguez
doaj   +1 more source

Radiotracers for the Central Serotoninergic System

open access: yesPharmaceuticals, 2022
This review lists the most important radiotracers described so far for imaging the central serotoninergic system. Single-photon emission computed tomography and positron emission tomography radiotracers are reviewed and critically discussed for each ...
Reynald Mangeant   +3 more
doaj   +1 more source

Comparative Evaluation of Antimicrobial Efficacy of Simvastatin Paste and Aloe Vera Paste as a Pulpotomy Medicament-An In-vitro Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Introduction: Pulpotomy is the complete removal of the coronal part of the dental pulp, followed by the application of an appropriate dressing or medicament to promote healing and maintain the viability of the teeth in the dental arch. Aloe vera has anti-
Sakshi Pravin Kabra, Nilima Thosar
doaj   +1 more source

Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles

open access: yesPharmaceutics, 2023
Despite their clinical success, Antibody-Drug Conjugates (ADCs) are still limited to the delivery of a handful of cytotoxic small-molecule payloads. Adaptation of this successful format to the delivery of alternative types of cytotoxic payloads is of ...
Victor Lehot   +10 more
doaj   +1 more source

Le médicament comme objet technique

open access: yesSocio-anthropologie, 2021
Since drugs are used not only to treat patients, but also to transform human performances, this paradigm shift in medical practice blurs the lines between therapeutic medicine and so-called ameliorative or augmentative medicine.
Daniela Cerqui, Margaux Bressan
doaj   +1 more source

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