Results 61 to 70 of about 18,955 (175)

Mass Spectrometry Imaging–Guided Proteomics, an Emerging Frontier in Spatial Biology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Spatial heterogeneity is a defining feature of tissue organization, yet conventional proteomic analysis provides limited information about the spatial origins of identified proteins. Spatially guided proteomics addresses this limitation by using tissue imaging techniques to select regions of interest (ROIs) for localized analysis by liquid ...
Kenneth Weke, Julian J. Lum, David R. Goodlett, Helena Pětrošová, Irena Dapic   +4 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

Engineering metal‐organic framework‐based smart porous nanoplatforms for targeted therapy and theranostic applications

Smart Molecules, EarlyView.
MOFs offer high porosity and tunability for biomedical applications, especially in cancer therapy via ROS generation and targeted delivery. Though toxicity, stability, and scalability remain key clinical challenges. Drug loading in MOFs exceeds 60%–70% with controlled release behavior.
Jagabandhu Bag, Subhasis Banerjee, Sabyasachi Banerjee, Sourav De, S. K. Ashok Kumar, Yan‐Jye Shyong, Subhankar Mukhopadhyay   +6 more
wiley   +1 more source

Évaluation de l'efficacité et de la tolérance d'un traitement radiochirurgical post opératoire par Gamma Knife des métastases cérébrales réséquées

, 2020
Contexte : la chirurgie associée à la radiothérapie pan cérébrale (RPC) est restée pendant longtemps le traitement standard pour la prise en charge des métastases cérébrales. Toutefois elle est associée à une toxicité neurocognitive importante.
Cantaloube, Marie
core  

Linear Accelerator–Based Stereotactic Body Radiotherapy of 36.25 Gy in Five Fractions for Localised Prostate Cancer: A Retrospective Single‐Institution Cohort Study

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Background Stereotactic body radiotherapy has become an established treatment option for localised prostate cancer. However, real‐world evidence from routine clinical practice remains limited, particularly in cohorts that include older patients.
Atsuto Katano, Hideomi Yamashita
wiley   +1 more source

Volumetric modulated arc radiosurgery for brain metastases from breast cancer: A single-center study. [PDF]

Colomb Med (Cali), 2021
Sánchez-Villalobos JM, Serna-Berna A, Salinas-Ramos J, Escolar-Pérez PP, Martínez-Alonso E, Achel DG, Alcaraz M.   +6 more
europepmc   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other embryonal tumors

Brain Pathology, EarlyView.
Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar, Maysa Al‐Hussaini, Vani Santosh, Vaishali Suri, Sung‐Hye Park, Yue‐Shan Piao, Tarik Tihan, Ho‐Keung Ng, Michael Buckland, Rakesh Jalali, Yonehiro Kanemura, Pieter Wesseling, Takashi Komori   +12 more
wiley   +1 more source

Involvement of the PRL-PAK1 Pathway in Cancer Cell Migration. [PDF]

Cancer Diagn Progn, 2023
Carrasco-Ceballos JM, Barrera-Hernández D, Locia-Espinosa J, Sampieri CL, Lara-Reyes JA, Hernández-Aguilar ME, Aranda-Abreu GE, Toledo-Cárdenas MR, Chi-Castañeda LD, Pérez-Estudillo CA, Rojas-Durán F.   +10 more
europepmc   +1 more source

Apprentissage automatique quantique et classique pour l’analyse d’images des tumeurs cérébrales

Brain tumor characterization using non-invasive techniques is eagerly needed. The objective of this thesis is to use advanced machine learning techniques and quantum technology on brain medical images to characterize brain tumors.
Felefly, Tony
core   +1 more source