Results 61 to 70 of about 12,466 (187)

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

open access: yesIbrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li   +10 more
wiley   +1 more source

Aumolertinib Versus Osimertinib as First‐Line Treatment for EGFR‐Mutant Non‐Small Cell Lung Cancer: A Retrospective Real‐World Multicenter Study

open access: yesInternational Journal of Cancer, EarlyView.
As third‐generation EGFR‐tyrosine kinase inhibitors, both aumolertinib and osimertinib demonstrate clinical efficacy for non‐small cell lung adenocarcinoma, especially in patients with brain metastases. Currently, head‐to‐head studies comparing these two agents in real‐world settings are scarce.
Jinxia Wang   +9 more
wiley   +1 more source

Analyse anatomo-clinique d'une série de métastases cérébrales de cancers colo-rectaux : impact des mutations de KRAS et de la localisation distale de la tumeur primitive [PDF]

open access: yes, 2022
Le cancer colorectal est une entité hétérogène, sur le plan clinico-pathologique mais également moléculaire, et les stratégies de traitement permettent actuellement des approches de plus en plus personnalisées.
Gras, Michaël
core  

Artificial intelligence driven diet‐intestinal microbiota‐host health integration: A four‐dimensional paradigm for advancing host wellness research

open access: yesiMetaOmics, EarlyView.
This graphical abstract presents a novel Diet‐Artificial Intelligence (AI)‐intestinal Microbiota–Host Health paradigm integrating microbiota‐centric pathways and an AI‐driven multi‐omics workflow. Diet shapes gut bacteria that regulate intestinal mucosal integrity, immune signaling, and gut–brain neurotransmitters to influence host health.
Tianle He   +16 more
wiley   +1 more source

Facteurs pronostiques des métastases cérébrales irradiées (étude rétrospective portant sur 250 patients traités au CHU d'Amiens entre 2001 et 2006) [PDF]

open access: yes, 2008
Introduction. Les métastases cérébrales sont une complication fréquente des cancers et leur survenue représente un tournant évolutif dans l histoire de la maladie.
ASSOULINE, Avi, KRZISCH, Claude
core  

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

open access: yesiNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu   +4 more
wiley   +1 more source

Investigation de la méthodologie radiomics dans le diagnostic différentiel précoce : radionécrose versus progression après radiothérapie stéréotaxique hypofractionnée d'oligo-métastases cérébrales [PDF]

open access: yes, 2018
CONTEXTE ET OBJECTIF DE L'ÉTUDE. La radiothérapie stéréotaxique (RTS) est recommandée dans le traitement des oligo-métastases cérébrales chez des patients avec une maladie extra-cérébrale contrôlée offrant un bon contrôle local.
Stefani, Anaïs
core  

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

open access: yesiNew Medicine, EarlyView.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng   +3 more
wiley   +1 more source

The Crude Venom of the Whitetail Lancehead, Bothrops leucurus, and Two of Its Enzymatic Components Are Selectively Cytotoxic for Glioma Cells In Vitro

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Malignant glioma is the most common primary brain tumor, and glioblastoma multiforme (GBM) remains its most aggressive and incurable form. Snake venoms contain bioactive compounds with promising antitumoral properties against several cancer types.
M. O. H. V. Rosário   +7 more
wiley   +1 more source

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