Results 61 to 70 of about 337 (107)

Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim   +16 more
wiley   +1 more source

Far‐infrared irradiation attenuates platelet‐derived growth factor‐stimulated vascular smooth muscle cell migration through protein phosphatase 2A‐mediated Akt inhibition

open access: yesPhotochemistry and Photobiology, EarlyView.
FIR irradiation enhances the physical association between Akt and PP2Ac in VSMCs, independent of the hyperthermal effect of FIR rays. The increased binding between Akt and PP2Ac induced by FIR irradiation facilitates the dephosphorylation of Akt at Ser473.
Na‐Young Lee   +5 more
wiley   +1 more source

History bias and its perturbation of the stimulus representation in the macaque prefrontal cortex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend During the execution of a distance discrimination task, we observed an interference from the most recently presented S2 stimulus on the current‐trial performance represented in the figure as weight on the arm of a balance. Specifically there was an attraction of the perceived magnitude of the first stimulus S1 towards the ...
Danilo Benozzo   +3 more
wiley   +1 more source

TUYỂN CHỌN GIỐNG MÔN ĐỐM VÀ MÔN CAO BẰNG PHƯƠNG PHÁP GÂY ĐỘT BIẾN CHIẾU XẠ

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2012
Trong thực tế, khoai môn được trồng và nhân giống vô tính, lai tạo giống hữu tính gặp nhiều trở ngại do cây ít khi ra hoa, thụ trái và tạo hạt tự nhiên.
Vũ Anh Pháp   +3 more
doaj  

Novel prognostication of patients with spinal and pelvic chondrosarcoma using deep survival neural networks

open access: yesBMC Medical Informatics and Decision Making, 2020
Background We used the Surveillance, Epidemiology, and End Results (SEER) database to develop and validate deep survival neural network machine learning (ML) algorithms to predict survival following a spino-pelvic chondrosarcoma diagnosis.
Sung Mo Ryu, Sung Wook Seo, Sun-Ho Lee
doaj   +1 more source

Robust activity‐dependent mitochondrial calcium dynamics at the AIS is dispensable for action potential generation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In cortical layer (L)5 pyramidal neurons we found that mitochondria in the axon initial segment (AIS) are distributed non‐uniformly and display robust calcium (Ca2+) uptake during action potential (AP) firing. Because the AIS is the site for the initiation of APs, which are shaped by cytosolic Ca2+ levels, we hypothesized that ...
Koen Kole, Maarten H.P. Kole
wiley   +1 more source

Prejudice as moral action in Christian ethical decision-making

open access: yesVerbum et Ecclesia, 2010
Given the many approaches regarding the use of the Bible, the ethical work in biblical interpretation and the work of being concerned with an ethical issue affecting the Christian as a moral agent cannot be separated from one another.
Stephanus J. Myburgh
doaj   +1 more source

Translational studies of chronic supplementation with a mitochondria‐targeted antioxidant to improve physical function with ageing

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Chronic oral supplementation with the mitochondria‐targeted antioxidant MitoQ (4 weeks; 250 µm) mitigates age‐related physical dysfunction in old mice, which is associated with reductions in skeletal muscle mitochondria‐specific superoxide and markers of mitochondrial reactive oxygen species (mitoROS)‐related oxidative stress and
Kevin O. Murray   +11 more
wiley   +1 more source

Rapid Local Recurrence of Breast Myoepithelial Carcinoma Arising in Adenomyoepithelioma: A Case Report

open access: yes대한영상의학회지, 2020
Adenomyoepithelioma (AME) is a rare breast neoplasm composed of both epithelial and myoepithelial cells with biphasic proliferation. Although most AMEs are benign, malignant transformation of either or both cellular components may occur.
Mo In Ha, Bo Kyoung Seo, Jung Woo Choi
doaj   +1 more source

Exploring the Impact of Authentic Leadership on Nurses' Organisational Citizenship Behaviour: Organisational Silence as a Mediator

open access: yesJournal of Advanced Nursing, Volume 82, Issue 4, Page 3019-3027, April 2026.
ABSTRACT Aim To investigate the relationship between nurse managers' authentic leadership and staff nurses' organisational citizenship behaviour and to explore the mediating roles of different types of organisational silence in the relationship. Design A cross‐sectional, correlational, descriptive design. Methods Survey data from 216 nurses across five
Hyun Ju Lho, Ja Kyung Seo, Seung Eun Lee
wiley   +1 more source

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