Results 11 to 20 of about 224 (111)

Computed tomography findings in horses presented with signs of head‐shaking

open access: yesEquine Veterinary Journal, Volume 55, Issue 4, Page 649-655, July 2023., 2023
Abstract Background Trigeminal nerve‐mediated head‐shaking (TNMH) in horses is a diagnosis made by exclusion. Computed tomography (CT) is frequently used to identify any disease process that could cause the clinical signs of head‐shaking. Although abnormalities are frequently identified, it is unknown whether treatment of these conditions improves ...
Melanie Perrier   +2 more
wiley   +1 more source

Effects of Etanercept on TNF‐α Inhibition in Rats with Adenine‐Induced Chronic Kidney Disease

open access: yesBioMed Research International, Volume 2022, Issue 1, 2022., 2022
Introduction. Chronic kidney disease (CKD) constitutes a chronic inflammatory state associated with an increase in inflammatory mediators and profibrotic molecules such as tumor necrosis factor‐α (TNF‐α). Etanercept (ETA) is a TNF inhibitor widely used in treatment of autoimmune inflammatory diseases.
Edgar Mendieta-Condado   +7 more
wiley   +1 more source

Assessment of Serum sRANKL, sRANKL/OPG Ratio, and Other Bone Turnover Markers with the Estimated 10‐Year Risk of Major and Hip Osteoporotic Fractures in Rheumatoid Arthritis: A Cross‐Sectional Study

open access: yesBioMed Research International, Volume 2021, Issue 1, 2021., 2021
Background. Fracture risk assessment tool (FRAX) index was developed for estimating of the 10‐year risk of major or hip osteoporotic fracture. To date, there is insufficient information regarding the correlation between FRAX and serum bone turnover markers (BTMs), such as soluble ligand of receptor activator of nuclear factor‐κB (sRANKL ...
C. A. Nava-Valdivia   +20 more
wiley   +1 more source

Polymorphism rs2073618 of the TNFRSF11B (OPG) Gene and Bone Mineral Density in Mexican Women with Rheumatoid Arthritis

open access: yesJournal of Immunology Research, Volume 2017, Issue 1, 2017., 2017
Osteoporosis (OP) is highly prevalent in rheumatoid arthritis (RA) and is influenced by genetic factors. Single‐nucleotide polymorphism (SNP) rs2073618 in the TNFRSF11B osteoprotegerin (OPG) gene has been related to postmenopausal OP although, to date, no information has been described concerning whether this polymorphism is implied in abnormalities of
C. A. Nava-Valdivia   +19 more
wiley   +1 more source

Inverse Relationship of the CMKLR1 Relative Expression and Chemerin Serum Levels in Obesity with Dysmetabolic Phenotype and Insulin Resistance

open access: yesMediators of Inflammation, Volume 2016, Issue 1, 2016., 2016
Background. In obesity there is a subclinical chronic low‐grade inflammatory response where insulin resistance (IR) may develop. Chemerin is secreted in white adipose tissue and promotes low‐grade inflammatory process, where it expressed CMKLR1 receptor.
Fernanda-Isadora Corona-Meraz   +13 more
wiley   +1 more source

The ‐174G/C Interleukin‐6 Gene Promoter Polymorphism as a Genetic Marker of Differences in Therapeutic Response to Methotrexate and Leflunomide in Rheumatoid Arthritis

open access: yesBioMed Research International, Volume 2016, Issue 1, 2016., 2016
Objective. To evaluate the association of ‐174G/C IL-6 polymorphism with failure in therapeutic response to methotrexate (MTX) or leflunomide (LEF). This prospective, observational cohort included 96 Mexican‐Mestizo patients with moderate or severe rheumatoid arthritis (RA), initiating MTX or LEF, genotyped for IL-6 ‐174G/C polymorphism by PCR‐RFLP ...
A. J. Ruiz-Padilla   +15 more
wiley   +1 more source

CCL2 Serum Levels and Adiposity Are Associated with the Polymorphic Phenotypes ‐2518A on CCL2 and 64ILE on CCR2 in a Mexican Population with Insulin Resistance

open access: yesJournal of Diabetes Research, Volume 2016, Issue 1, 2016., 2016
Genetic susceptibility has been described in insulin resistance (IR). Chemokine (C‐C motif) ligand‐2 (CCL2) is overexpressed in white adipose tissue and is the ligand of C‐C motif receptor‐2 (CCR2). The CCL2 G‐2518A polymorphism is known to regulate gene expression, whereas the physiological effects of the CCR2Val64Ile polymorphism are unknown. The aim
Milton-Omar Guzmán-Ornelas   +10 more
wiley   +1 more source

Prevalencia de trastornos músculo-esqueléticos en el personal de esterilización en tres hospitales públicos

open access: yesMedicina y Seguridad del Trabajo, 2014
Introducción: Los trastornos músculo-esqueléticos, según informe de la agencia Europea para la Seguridad y Salud en el Trabajo, constituyen el problema de salud laboral más común en Europa.
Rosa María Rosario Amézquita   +1 more
doaj   +1 more source

Low CD36 and LOX‐1 Levels and CD36 Gene Subexpression Are Associated with Metabolic Dysregulation in Older Individuals with Abdominal Obesity

open access: yesJournal of Diabetes Research, Volume 2016, Issue 1, 2016., 2016
Background. Obesity study in the context of scavenger receptors has been linked to atherosclerosis. CD36 and LOX‐1 are important, since they have been associated with atherogenic and metabolic disease but not fat redistribution. The aim of our study was to determinate the association between CD36 and LOX‐1 in presence of age and abdominal obesity ...
Perla-Monserrat Madrigal-Ruíz   +10 more
wiley   +1 more source

The 482Ser of PPARGC1A and 12Pro of PPARG2 Alleles Are Associated with Reduction of Metabolic Risk Factors Even Obesity in a Mexican‐Mestizo Population

open access: yesBioMed Research International, Volume 2015, Issue 1, 2015., 2015
The aim of this study was to investigate the relationship between functional polymorphisms Gly482Ser in PPARGC1A and Pro12Ala in PPARG2 with the presence of obesity and metabolic risk factors. We included 375 individuals characterized as Mexican‐Mestizos and classified by the body mass index (BMI).
Mónica Vázquez-Del Mercado   +8 more
wiley   +1 more source

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