Results 41 to 50 of about 865,609 (245)

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

Doubly weighted M-estimation for nonrandom assignment and missing outcomes

Journal of Causal Inference
This article proposes a class of M-estimators that double weight for the joint problems of nonrandom treatment assignment and missing outcomes. Identification of the main parameter of interest is achieved under unconfoundedness and missing at random ...
Negi Akanksha
doaj   +1 more source

Bayesian inference and prediction in multi-server Markovian queueing system with reverse balking: A simulation-based approach

Statistical Theory and Related Fields
This article presents an in-depth exploration of classical and Bayesian inference methods to estimate the traffic intensity parameter, providing a comprehensive comparison of these two statistical paradigms in a novel multiserver Markovian queueing model
Asmita Tamuli, Dhruba Das
doaj   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Optimizing precision farming: enhancing machine learning efficiency with robust regression techniques in high-dimensional data

Journal of Nigerian Society of Physical Sciences
Smart precision farming leverages IoT, cloud computing, and big data to optimize agricultural productivity, lower costs, and promote sustainability through digitalization and intelligent methodologies.
Nour Hamad Abu Afouna, Majid Khan Majahar Ali   +1 more
doaj   +1 more source

A Noise Robust Micro-Range Estimation Method for Precession Cone-Shaped Targets

Remote Sensing, 2021
The estimation of micro-Range (m-R) is important for micro-motion feature extraction and imaging, which provides significant supports for the classification of a precession cone-shaped target.
Zhenyu Zhuo, Yu Zhou, Lan Du, Ke Ren, Yi Li   +4 more
doaj   +1 more source

On Catoni's M-Estimation

, 2022
Catoni proposed a robust M-estimator and gave the deviation inequality for one fixed test function. The present paper is devoted to the uniform concentration inequality for a family of test functions. As an application, we consider empirical risk minimization for heavy-tailed losses.
Li, Pengtao, Wang, Hanchao
openaire   +2 more sources

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Robust M-Estimators on Spheres

Journal of Multivariate Analysis, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ko, D.J., Chang, T.
openaire   +2 more sources

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane, Wei Xue, Amira Qumseya, Thomas Scharschmidt, Kathryn R. Tringale, Oscar Lopez Nunez, Jiaqi Hu, Donald A. Barkauskas, Rajkumar Venkatramani, Sheri L. Spunt, Aaron R. Weiss, Noah C. Federman   +11 more
wiley   +1 more source