Results 81 to 90 of about 865,609 (245)

Improved regression in ratio type estimators based on robust M-estimation. [PDF]

PLoS One, 2022
Rather KUI, Koçyiğit EG, Onyango R, Kadilar C.   +3 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Edge-preserving smoothing filter using fast M-estimation method with an automatic determination algorithm for basic width. [PDF]

Sci Rep, 2023
Yamaguchi Y, Yoshida I, Kondo Y, Numada M, Koshimizu H, Oshiro K, Saito R.   +6 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A Method of m-Point Sinusoidal Signal Amplitude Estimation

Measurement Science Review, 2016
The paper presents a new and original method of m-point estimation of sinusoidal signal amplitude. In this method, an m-point estimator is calculated on the basis of m initial signal samples. The way the estimator is constructed is explained. It is shown
Sienkowski Sergiusz
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Signal-to-noise ratio estimation for M-QAM signals in η−μand κ−μfading channels

EURASIP Journal on Advances in Signal Processing, 2019
In this paper, signal-to-noise ratio (SNR) estimation is carried out by the method of moments (MOM) for fading channels modeled by probability distributions η−μ and κ−μ, considering M-ary quadrature amplitude modulation (M-QAM) with constellation energy ...
Wamberto José Lira de Queiroz, Danilo Brito Teixeira de Almeida, Francisco Madeiro, Waslon Terllizzie Araújo Lopes   +3 more
doaj   +1 more source

Optimal Robust M-Estimates of Location

The Annals of Statistics, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Fraiman, Ricardo, Yohai, Víctor J., Zamar, Ruben H.   +2 more
openaire   +3 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source