Objective JAK inhibitors (JAKis) have shown promising effects in early‐phase studies of SSc. We aimed to assess the safety and explore effectiveness of JAKis compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the EUSTAR cohort was performed.
Stefano Di Donato +27 more
wiley +1 more source
What makes them stick? A genetic analysis of biofilm formation of an infective endocarditis-causing <i>Streptococcus canis</i> strain using transposon directed insertion-site sequencing. [PDF]
Katsburg M +6 more
europepmc +1 more source
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source
Protocol for natural and biomedical image processing in the hypercomplex domain using the 2D orthogonal planes split. [PDF]
Valous NA +14 more
europepmc +1 more source
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt +8 more
wiley +1 more source
Correction to "Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-κB-Dependent Mechanism". [PDF]
europepmc +1 more source
Singletrack: an algorithm for improving memory consumption and performance of gap-affine sequence alignment. [PDF]
López-Villellas L +7 more
europepmc +1 more source
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi +3 more
wiley +1 more source
The peroxisomal importomer can accommodate an intrinsically disordered protein of 1247 residues. [PDF]
Pedersen MP +3 more
europepmc +1 more source
Laser Powder Bed Fusion of Alumina: Effects of Scanning Strategies on External and Internal Defects
This study investigates how scanning strategies affect pure alumina in laser powder bed fusion. Linear 45° scanning yields uniform surfaces but high porosity, while the island‐concentric strategy provides higher density with through‐holes favorable for infiltration. Findings highlight pathways toward optimizing defect‐free alumina parts.
Mohamed Abdelmoula +7 more
wiley +1 more source

