Results 11 to 20 of about 24,015,312 (122)

A Versatile and Robust Platform for the Scalable Manufacture of Biomimetic Nanovaccines. [PDF]

Adv Sci (Weinh), 2021
Flash nanocomplexation (FNC) is exploited to produce cell membrane‐biomimetic nanotherapeutics in a robust, versatile, reproducible, and scalable manner. Cancer cell membrane‐coated, CpG‐loaded mesoporous silica nanoparticles fabricated using FNC exhibit better lymph node targeting, T‐cell activation, anticancer immunoresponse, and combined ...
Hu H, Yang C, Zhang F, Li M, Tu Z, Mu L, Dawulieti J, Lao YH, Xiao Z, Yan H, Sun W, Shao D, Leong KW.   +12 more
europepmc   +2 more sources

Consistent Intraocular Pressure Reduction by Solid Drug Nanoparticles in Fixed Combinations for Glaucoma Therapy. [PDF]

Adv Sci (Weinh)
Using a scalable method for fabricating solid drug nanoparticles (SDNs), SDNs in fixed combination of the hydrophobic antiglaucoma drugs brimonidine (BM) and betaxolol (BX) are consistently produced. These SDNs demonstrated enhanced ocular permeation and sustained intraocular pressure reduction, indicating their effectiveness for glaucoma therapy ...
Huang D, Norat P, Qi L, Chernatynskaya A, Cole JD, Mani VJ, Xu L, Liu X, Yang H, Yang H.   +9 more
europepmc   +2 more sources

Nanocarrier‐Based Drug Delivery Systems using Microfluidic‐Assisted Techniques

Advanced NanoBiomed Research, Volume 3, Issue 11, November 2023., 2023
This research reviews the progress of nanocarrier‐facilitated microfluidic‐based and organ‐on‐a‐chip‐modeled microfluidic nanodrug delivery systems in clinical translation. Different factors and challenges that hinder a drug delivery system, from its conception to experimental validation and start‐up investment to commercialization for clinical ...
Md. Kowsar Alam
wiley   +1 more source

‘I'm still a woman’: A qualitative study on sexuality in heterosexual women with Turner Syndrome

Journal of Clinical Nursing, Volume 32, Issue 17-18, Page 6634-6647, September 2023., 2023
Abstract Aim and objectives The aim of this study was to describe and understand how heterosexual women with Turner Syndrome experience sexuality. Background Turner Syndrome is a genetic condition that is the result of one of the X chromosomes missing or partially missing, and it affects women of all ages.
José Granero‐Molina, Rocío Aguirre Román, María del Mar Jiménez‐Lasserrotte, María Dolores Ruiz‐Fernández, María Isabel Ventura‐Miranda, Gonzalo Granero‐Heredia, Isabel María Fernández‐Medina   +6 more
wiley   +1 more source

Single‐cell RNA‐sequencing of retrieved human oocytes and eggs in clinical practice and for human ovarian cell atlasing

Molecular Reproduction and Development, Volume 89, Issue 12, Page 597-607, December 2022., 2022
Abstract With the advancement of single‐cell separation techniques and high‐throughput sequencing platforms, single‐cell RNA‐sequencing (scRNA‐seq) has emerged as a vital technology for understanding tissue and organ systems at cellular resolution. Through transcriptional analysis, it is possible to characterize unique or rare cell types, interpret ...
Jordan H. Machlin, Ariella Shikanov
wiley   +1 more source

Microfluidic Nanoparticles for Drug Delivery

Small, Volume 18, Issue 36, September 8, 2022., 2022
Microfluidics offers a promising strategy for making nanoparticles for drug delivery due to its capability in precisely controlling nanoparticle properties. This article provides a critical review of recent progress in microfluidic nanoparticles for drug delivery.
Yun Liu, Guangze Yang, Yue Hui, Supun Ranaweera, Chun‐Xia Zhao   +4 more
wiley   +1 more source

Hepatic-Accumulated Obeticholic Acid and Atorvastatin Self-Assembled Nanocrystals Potentiate Ameliorative Effects in Treatment of Metabolic-Associated Fatty Liver Disease. [PDF]

Adv Sci (Weinh)
A hepatic‐targeted nanodrug composed of obeticholic acid (OCA) and atorvastatin (AHT) is created to improve the stability in gastroenteric environments, while leveraging hepatic accumulation through apical sodium‐dependent bile acid transporter. Oral administration of the nanodrug outperforms the simple combination of OCA and AHT in ameliorating liver ...
Lu H, Ban Z, Xiao K, Sun M, Liu Y, Chen F, Shi T, Chen L, Shao D, Zhang M, Li W.   +10 more
europepmc   +2 more sources

Application of the Molecular Interaction Volume Model for Calculating Activities of Elements in Ferromanganese Alloys: Mn-C, Mn-Fe, Fe-C, and Mn-Fe-C Systems

, 2022
The molecular interaction volume model (MIVM) developed by Tao is a fluid-based model derived from statistical thermodynamics and fluid phase equilibria.
Junhong Zhang, Haipeng Chen, Wenlong Zhan, Zhijun He, Lihua Gao   +4 more
core   +1 more source

Nanoparticles Based on Hydrophobic Polysaccharide Derivatives—Formation Principles, Characterization Techniques, and Biomedical Applications

Macromolecular Bioscience, Volume 20, Issue 4, April 2020., 2020
A comprehensive overview is presented about polysaccharide nanoparticles that are obtained by nano‐self‐assembly of hydrophobic polysaccharide derivatives. It is demonstrated how these particles can be prepared by various techniques and how their properties can be altered.
Martin Gericke, Peter Schulze, Thomas Heinze   +2 more
wiley   +1 more source

Self-assembling process of flash nanoprecipitation in a multi-inlet vortex mixer to produce drug-loaded polymeric nanoparticles [PDF]

, 2011
We present an experimental study of self-assembled polymeric nanoparticles in the process of flash nanoprecipitation using a multi-inlet vortex mixer (MIVM).
Seungpyo Hong (182769), Robert Prud'homme (8002382), Ying Liu (18461), Hao Shen (195461)   +3 more
core   +3 more sources