Results 1 to 10 of about 1,454 (106)

A scalable human gut-immune co-culture model for evaluating inflammatory bowel disease anti-inflammatory therapies [PDF]

open access: yesSLAS Discovery
Current treatments for inflammatory bowel disease (IBD) are often ineffective long-term, as many patients ultimately become unresponsive to anti-inflammatory drugs. The need for improved therapeutics is urgent. Animal models utilized for drug development
Swetha Peddibhotla   +4 more
doaj   +2 more sources

Fomite workshop recommendations addressing the role of surfaces in virus transmission in the built environment [PDF]

open access: yesmSphere
The emergence of SARS-CoV-2 has led to a need to assess the role of fomites in viral transmission within the built environment. Assessing the role of fomites is necessary for developing intervention strategies for controlling emerging pathogens. A fomite
Sarah E. Abney   +21 more
doaj   +2 more sources

Five‐year assessment of wolf translocation to Isle Royale National Park, 2018–2023

open access: yesConservation Science and Practice
Gray wolf (Canis lupus) translocation is a common approach for restoring ecological function through top‐down regulation. Understanding the processes that contribute to successful wolf translocations is essential for planning future restorations.
Adia R. Sovie   +12 more
doaj   +2 more sources

Insights from the trial innovation network’s initial consultation process [PDF]

open access: yesJournal of Clinical and Translational Science
Multicenter clinical trials are essential for evaluating interventions but often face significant challenges in study design, site coordination, participant recruitment, and regulatory compliance.
Paul A. Harris   +44 more
doaj   +2 more sources

José Villegas Cordero (1844-1921) y Estados Unidos: retratos, murales y un libro de viaje

open access: yesArchivo Español de Arte, 2022
Con este artículo se estudia la figura de José Villegas Cordero y su relación con varias personas procedentes de Estados Unidos. Villegas fue maestro y amigo de John Elliott, a quien guio en su producción artística. Maud Howe, esposa de Elliott, reflejó
Victoria Sánchez Mellado   +1 more
doaj   +1 more source

Severe COVID-19 Is Associated With an Altered Upper Respiratory Tract Microbiome

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
BackgroundThe upper respiratory tract (URT) is the portal of entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and SARS-CoV-2 likely interacts with the URT microbiome.
Meghan H. Shilts   +26 more
doaj   +1 more source

Quantifying anthropogenic wolf mortality in relation to hunting regulations and landscape attributes across North America

open access: yesEcology and Evolution, 2022
Understanding the types and magnitude of human‐caused mortality is essential for maintaining viable large carnivore populations. We used a database of cause‐specific mortality to examine how hunting regulations and landscape configurations influenced ...
Jacob E. Hill   +15 more
doaj   +1 more source

What Is the Role of Patriotism in the Study of American Art?

open access: yesPanorama, 2017
Do we have a responsibility to the nation in our teaching and writing on American art? How would this responsibility be enacted and can it be done without seeming to be jingoistic?
M. Elizabeth Boone, Lauren Lessing
doaj   +1 more source

Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets

open access: yesNature Communications, 2021
The analysis of essential genes in pathogens can be used to discover potential antimicrobial targets. Here, the authors use a machine learning model and chemogenomic analyses to generate genome-wide gene essentiality predictions for the fungal pathogen ...
Ci Fu   +22 more
doaj   +1 more source

The Paintings Left Behind: Two New Paintings by Mary Cassatt from Seville

open access: yesPanorama, 2018
Boarding a train toward an affluent suburb northeast of Madrid, I wondered what this journey would bring. I had been contacted a little over a year earlier by a person who claimed to have two paintings by Mary Cassatt (1844–1926).
M. Elizabeth Boone
doaj   +1 more source

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