Results 171 to 180 of about 133,217 (289)

Longitudinal real-time PCR monitoring of CMV DNAemia and renal function in living-donor kidney transplant recipients with low immunological risk. [PDF]

BMC Nephrol
Gülteki̇n M, Çakmak E, Bulut A.
europepmc   +1 more source

Dynamic Blanket Stress Test — M0 (DBST-M0)

DBST-M0 is a pre-registered toy computational experiment testing whether a bounded relevance-boundary architecture shows rising maintenance pressure and/or adequacy loss relative to an unconstrained greedy relevance architecture as the rate of shared ...
John Silliphant
core  

In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma

Advanced Science, EarlyView.
By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He, Duo Yu, Fei Xie, Kaisheng Hou, Zhaozhao Li, Meifang Dai, Jingyi Yun, Haiyan Cao, Yang Xiao, Yueyuan Qiu, Gege Shi, Wangqian Zhang, Shuning Wang, Qiang Hao, Jieyu Zhang, Zhaowei Wang, Yingqi Zhang, Kuo Zhang, Jintao Gu, Haichen Du, Meng Li   +20 more
wiley   +1 more source

Integrated Transcriptomic and Metabolomic Analysis Reveals MeJA-Mediated Flavonoid Biosynthesis in <i>Cyclocarya paliurus</i> Callus. [PDF]

Plants (Basel)
Gao Y, Gao K, Wang Y, Li Z, Qin J, Shang X.   +5 more
europepmc   +1 more source

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu, Shu‐Hui Lv, Shui‐Qing He, Yao‐Fei Jiang, Xing‐Si Peng, Jian‐Cong Sun, Fen He, Hai‐Yan Qin, Nian Lu, Wei‐Xin Bei, Lin‐Yu Zhao, Wan‐Qin Shen, Ze‐Yu Zhao, Lin Wang, Yan‐Qun Xiang, Wang‐Zhong Li   +15 more
wiley   +1 more source

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

BJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek, M. Almquist, A. O. Bergenfelz, T. J. Musholt, E. Nordenström, on behalf of the EUROCRINE® Council, M. Almquist, M. Barczynski, L. Brunaud, T. Clerici, M. H. Hansen, M. Iacobone, Ö. Makay, F. F. Palazzo, N. Muñoz‐Pérez, M. Raffaelli, P. Riss, S. van Slycke, M. R. Vriens   +18 more
wiley   +1 more source

Tumor-educated macrophages promote ferroptosis inhibition in pancreatic cancer via activating the p62-KEAP1-NRF2 pathway. [PDF]

Front Immunol
Li S, Qi D, Yi H, Yang L, Xu T, Zhou W, Xu W, Xu Z, Tang H, Xie F, Zhang C, Liang X.   +11 more
europepmc   +1 more source

Interfacial and Hydration‐Associated Lithium Retention During FePO4 Regeneration from Spent LiFePO4 Cathodes

Advanced Science, EarlyView.
During iron phosphate regeneration, sequential washing distinguishes lithium fractions by accessibility: approximately 70% of precipitate‐associated lithium is washing‐removable, while approximately 30% remains after three cycles. Comparisons of simulated and practical systems associate retained lithium with hydrated amorphous Fe‐O‐P environments ...
Fei Han, Langyi Xiao, Genping Yi, Tian Liu, Shoudong Huang, Haonan Yan, Guang Yang, Liming Yang, Xubiao Luo   +8 more
wiley   +1 more source

Enhanced tumor metastasis driven by the crosstalk between melanoma cells and tumor-associated macrophages: insights into the CXCL10/CXCR3-hnRNP C-MIF axis. [PDF]

J Immunother Cancer
Wang Y, Massa C, Tammineni GC, Ulagappan K, Yang B, Kokoretsis D, Zhao Y, Subbarayan K, Seliger B.   +8 more
europepmc   +1 more source

Tip60‐Mediated USP22 Lactylation Drives Glutamine Metabolic Reprogramming via SLC25A5 in TNBC

Advanced Science, EarlyView.
Tip60‐mediated USP22 K134 lactylation, stabilizing SLC25A5 to enhance glutamine metabolism and α‐KG secretion. The secreted α‐KG drives GPR91‐dependent M2 macrophage polarization, promoting triple‐negative breast cancer progression. Targeting this axis synergizes with CB‐839, offering a promising therapeutic strategy for TNBC.
Fang Zhen, Hongyi Wang, Ningzhi Zhang, Le Wang, Huiyuan Tian, Luxi Kang, Zhanpeng Liu, Jing Hu   +7 more
wiley   +1 more source