Results 221 to 230 of about 133,217 (289)

Age‐Associated B Cells Contribute to Inflammation Via Antibody‐Independent Mechanisms in Takayasu Arteritis

Arthritis &Rheumatology, EarlyView.
Objective Although Takayasu arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B cell activation and its contributions to TAK pathogenesis. Methods Histologic analysis of paravascular lymph nodes and affected arteries was conducted
Chenglong Fang, Xiaoxi Yang, Xiaochuan Sun, Shangyi Jin, Lihong Du, Jinwei Gao, Jing Li, Zhen Chen, Yuexin Chen, Mengtao Li, Xinping Tian   +10 more
wiley   +1 more source

Decreased expression of immune activator WARS1 and other pro-inflammatory mediators in type 1-like macrophages as an associated mode of action in response to fucoidan from marine brown algae. [PDF]

Front Immunol
Ostermann J, Gemoll T, Schnüttgen T, Tischhöfer MT, Plötze-Martin K, Fleckner J, Bruchhage KL, Alban S, Pries R.   +8 more
europepmc   +1 more source

Risk of Cancer According to Duration of Targeted Therapy Exposure in Spondyloarthritis: A Nationwide Cohort Study From the French Health Insurance Database

Arthritis &Rheumatology, EarlyView.
Objective To assess the association between duration of targeted therapy exposure and cancer risk in patients with spondyloarthritis (SpA), including those with psoriatic arthritis, axial SpA, and other subtypes. Methods This nationwide cohort study used the French health insurance database to identify adults with SpA initiating a targeted therapy ...
Karine Tankovic, Pascal Claudepierre, Tat Thang Vo, Tran Trong Khoi Le, Siham Iggui, Laetitia Penso, Emilie Sbidian, Laura Pina Vegas   +7 more
wiley   +1 more source

A pancreatic cancer organoid-macrophage co-culture using starPEG-heparin hydrogel deciphers tumor-immune cell interactions. [PDF]

NPJ Precis Oncol
Thyen J, Sioson VA, Haak D, Jahnke B, Fusenig M, Aftab AM, Stammberger A, Brückmann S, Polster H, Hübner S, Kast VJ, Pfeifer M, Prause R, Mittné V, Beer C, Reinhart MH, Seifert AM, Seifert L, Bornhäuser M, Werner C, Schmitz M, Aust DE, Weitz J, Loessner D, Stange DE, Poetsch AR, Pecqueux M, Baenke F.   +27 more
europepmc   +1 more source

Fibroproliferative Remodeling of Immune‐Vascular Co‐Culture Spheroid Models in Response to Atherogenic Stimulation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Cell‐based models are highly valuable platforms for preclinical studies of atherosclerosis, offering controllable environments to investigate disease mechanisms. Three‐dimensional (3D) spheroids, a class of cell‐based models, enable the study of atherosclerotic disease phenomena under physiologically relevant yet controlled conditions. In this
Ibukunoluwa Naiyeju, Stephanie Lehoux, Maryam Tabrizian   +2 more
wiley   +1 more source

Bioactive Profile, Antioxidant, and <i>In Vitro</i> Antimicrobial Activity of 'Mortiño' (<i>Vaccinium meridionale</i>) and Other <i>Rubus</i> and <i>Vaccinium</i> Andean Red Fruits at Different Stages of Ripeness. [PDF]

Antioxidants (Basel)
Coyago-Cruz E, Méndez G, Escobar-Quiñonez R, Cisneros G, Heredia-Moya J.   +4 more
europepmc   +1 more source

Combinatorial effects of curcumin, morin, and phyllanthin in MDA-MB-231 and MCF-7 breast cancer cell lines. [PDF]

Indian J Pharmacol
Vuppaladadium S, Xavier J, Kumar AK, Annamaneni S.   +3 more
europepmc   +1 more source

A Study of Coming Generation NK-M0 Ships

JOURNAL OF THE MARINE ENGINEERING SOCIETY IN JAPAN, 1984
Ohashi, Masaru, Yamada, Hiroshi, Ishida, Kenji   +2 more
openaire   +2 more sources

Blood Eosinophils From CRSwNP Patients Present Higher CCR3 Expression Associated With Olfactory Recovery After Treatment With Dupilumab

International Forum of Allergy &Rhinology, EarlyView.
Emeline Delaunay, Stephane Esnault, Arnaud Dendooven, Jacques Trauet, Céline Desvant, Guillaume Lefèvre, Geoffrey Mortuaire   +6 more
wiley   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source