ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett+4 more
wiley +1 more source
Nitro-Oleic acid protects from neovascularization, oxidative stress, gliosis and neurodegeneration in oxygen-induced retinopathy. [PDF]
Victoria VM+6 more
europepmc +1 more source
ABSTRACT The study aims to investigate factors within the double ABC‐X model to explain parents' stress during the first wave of the COVID‐19 pandemic, with a focus on adaptive resources (i.e., parent–child relationship and relationship quality) and the moderating effect of appraisal (i.e., family resilience beliefs).
Anis Ben Brik, Yunqi Wang
wiley +1 more source
α-Lipoic acid alleviate myocardial infarction by suppressing age-independent macrophage senescence. [PDF]
Wang Y+8 more
europepmc +1 more source
ABSTRACT This study investigated family mechanisms through which pandemic stressors affect parental stress using the Double ABC‐X model of family stress and adaptation. Specifically, this study examines the moderated mediation effects to test the conditional indirect influence of a moderating variable (i.e., family resilience beliefs) on the ...
Anis Ben Brik
wiley +1 more source
Longitudinal bidirectional association between psychosocial function and depression in Chinese patients with clinically remitted depression: a cross-lagged panel model analysis. [PDF]
Wenyan H+6 more
europepmc +1 more source
Necessary but not Sufficient: Limitations of Projection Quality Metrics
Abstract High‐dimensional data analysis often uses dimensionality reduction (DR, also called projection) to map data patterns to human‐digestible visual patterns in a 2D scatterplot. Yet, DR methods may fail to show true data patterns and/or create visual patterns that do not represent any data patterns.
A. Machado, M. Behrisch, A. Telea
wiley +1 more source
A Pathophysiologically Hypertrophic 3T3-L1 Cell Model-An Alternative to Primary Cells Isolated from DIO Mice. [PDF]
Kaczmarek I+4 more
europepmc +1 more source
Sirt3 Rescues Porphyromonas gingivalis‐Impaired Cementogenesis via SOD2 Deacetylation
Sirt3 deacetylated SOD2 via K68 to orchestrate P.g.‐impaired cementogenesis. Reestablishment of the Sirt3/SOD2 axis by honokiol reduced SOD2 acetylation and facilitated cementogenesis. ABSTRACT The keystone pathogen Porphyromonas gingivalis (P.g.) is responsible for cementum resorption in periodontitis; however, the mechanism involved in it remains ...
Xin Huang+6 more
wiley +1 more source
Balancing Anti-Inflammation and Neurorepair: The Role of Mineralocorticoid Receptor in Regulating Microglial Phenotype Switching After Traumatic Brain Injury. [PDF]
Zhang B+8 more
europepmc +1 more source