Results 171 to 180 of about 45,204 (255)

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

The PTBP1-EZH2-DOCK2 axis promotes M1 microglial polarization and exacerbates neuronal apoptosis following spinal cord injury. [PDF]

J Orthop Translat
Sha C, Pan F, Liu X, Wang Z, Dai H, Huang K.   +5 more
europepmc   +1 more source

Efficacy of House Dust Mite Immunotherapy in Chinese Allergic Rhinitis Patients With Diverse Sensitization Patterns: A Multicenter Study (COVER Study)

Allergy, EarlyView.
This prospective multicenter study corroborates the efficacy of AIT with the native HDM allergen extract in Chinese AR patients with diverse HDM sensitization patterns. HDM sensitization pattern affects the efficacy of AIT, with patients sensitized to both major and minor allergens of HDM showing improved outcomes with HDM SCIT.
Qingxiu Xu, Xuan Yuan, Wang Liao, Hao Chen, Qing Jiang, Lin Yang, Jin Liu, Le Li, Nan Huang, Wenjing Li, Yaqi Yang, Dongxia Ma, Jun Bai, Zhihai Xie, Rongfei Zhu   +14 more
wiley   +1 more source

Causal modeling reveals cell-cell communication dynamics in the tumor microenvironment during anti-PD-1 therapy in breast cancer patients. [PDF]

Brief Bioinform
Qiu A, Zhang H, Ramsey JD, Andrews B, Sun B, Ren S, Lu M, Zhang K, Cooper GF, Lu B, Chen L, Lu X.   +11 more
europepmc   +1 more source

Pig Seminal Plasma Extracellular Vesicles Enhance Motility During Preservation of Epididymal Spermatozoa but Impair Capacitation and IVF Parameters

Andrology, EarlyView.
ABSTRACT Background Extracellular vesicles (EVs) produced by accessory sex glands play a key role in sperm functionality, influencing motility, viability, acrosome integrity, metabolic activity, and capacitation. Most studies on the effects of EVs on spermatozoa have focused on ejaculated spermatozoa, which have already been exposed to their own native
Ana Moya‐Fernández, Santa María Toledo‐Guardiola, Peter Silke, Sergio Navarro‐Serna, Carmen Matás   +4 more
wiley   +1 more source

Bacteroides coprocola protects dopaminergic neurons in rotenone-induced Parkinson's disease mouse model by modulating gut microbiota dysbiosis and inhibiting the NLRP3 signaling pathway. [PDF]

Transl Neurodegener
Liu Z, Nie J, Li Y, Huang M, Chen Z, Yu S, Zheng J, Tan Y, Chen S.   +8 more
europepmc   +1 more source

Can Technological and Customer Competencies Enable the Firm to Be Greener? Simultaneous Consideration of Resource‐Based View and Social License to Operate

Business Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT This research explores the contribution of firm competencies and green management practices to enhancing a firm's sustainable performance. It examines the effects of technological competencies (TC) and customer competencies (CC) through the lens of a competence‐based view (CBV) framework, particularly focusing on their influence on green ...
Tongkyu Kim, Hyeonyu Son, Yu Ri Kim, Jiyeon Han, Yunze Cho, Taewoo Roh   +5 more
wiley   +1 more source

Fra pessimisme til sosialistisk realisme. Symfonikeren Nikolaj Mjaskovskij (1881–1950). Del 1

Studia Musicologica Norvegica, 2018
Asbjørn Ø. Eriksen
doaj   +1 more source

Structural Characterization and Anti-Colitis Mechanisms of <i>Polygonatum sibiricum</i> Polysaccharides via Modulation of Neutrophil Extracellular Traps (NETs)-Macrophage Crosstalk. [PDF]

Nutrients
Xu J, Zheng J, Ke W, Qiu Y, Zhang L, Wu C, Zhang X, Xia D, Li F.   +8 more
europepmc   +1 more source

Using multilabel classification neural network to detect intersectional DIF with small sample sizes

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract This study introduces InterDIFNet, a multilabel classification neural network for detecting intersectional differential item functioning (DIF) in educational and psychological assessments, with a focus on small sample sizes. Unlike traditional marginal DIF methods, which often fail to capture the effects of intersecting identities and require ...
Yale Quan, Chun Wang
wiley   +1 more source