The association between radiation dermatitis severity and social integration among patients with head and neck cancer undergoing radiotherapy: Statistical mediation by mood states. [PDF]
Wang Y, Xu Y, Ji M, Bai X.
europepmc +1 more source
Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan +16 more
wiley +1 more source
Tryptophan-Restricted Intermittent Diet Alleviates Estrogen Deficiency-Induced Osteoporosis via Regulating Coupling Effects of "Gut-Bone" Axis. [PDF]
Xiang T +12 more
europepmc +1 more source
Using multilabel classification neural network to detect intersectional DIF with small sample sizes
Abstract This study introduces InterDIFNet, a multilabel classification neural network for detecting intersectional differential item functioning (DIF) in educational and psychological assessments, with a focus on small sample sizes. Unlike traditional marginal DIF methods, which often fail to capture the effects of intersecting identities and require ...
Yale Quan, Chun Wang
wiley +1 more source
Neuronal exosomal miR-25-3p attenuates M1 microglial activation and neurotoxicity by targeting TLR4 to regulate the NF-κB signaling pathway. [PDF]
Hu G, Sarulatuya, Du S, Huang Z, Tang X.
europepmc +1 more source
The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu +11 more
wiley +1 more source
Multi-omics reveals CXCR4 drives immune escape in colorectal cancer via metabolic reprogramming and immune microenvironment remodeling. [PDF]
Zhu C +12 more
europepmc +1 more source
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo +7 more
wiley +1 more source

