Results 91 to 100 of about 104,480 (306)
Bankruptcy or default is a situation, in which, a business company or enterprise gets unable to pay its debts and cannot meet its obligations. Different reasons can cause bankruptcy that mismanagement seems to be one of the most important reasons for ...
Faghekarimi Shahriar +3 more
doaj +1 more source
Biophysical characterization of naturally occurring titin M10 mutations [PDF]
AbstractThe giant proteins titin and obscurin are important for sarcomeric organization, stretch response, and sarcomerogenesis in myofibrils. The extreme C‐terminus of titin (the M10 domain) binds to the N‐terminus of obscurin (the Ig1 domain) in the M‐band. The high‐resolution structure of human M10 has been solved, along with M10 bound to one of its
Michael W, Rudloff +2 more
openaire +2 more sources
Generalized complex geometry of pure backgrounds in ten and eleven dimensions
Pure backgrounds are a natural generalization of supersymmetric Calabi-Yau compactifications in the presence of flux. They are described in the language of generalized SU(d) x SU(d) structures and generalized complex geometry, and they exhibit some ...
Prins, Daniël, Tsimpis, Dimitrios
core +3 more sources
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson +11 more
wiley +1 more source
PRODUKSI ANTIBIOTIKA OLEH Bacillus subtilis M10 DALAM MEDIA UREA-SORBITOL
PRODUCTION OF ANTIBIOTICS BY Bacillus subtilis M10 IN UREA-SORBITOL MEDIUM. Infection diseases still become the main health problems that suffered by people in Indonesia.
Supartono Supartono +3 more
doaj +1 more source
Galactic fountains and the rotation of disc-galaxy coronae [PDF]
In galaxies like the Milky Way, cold (~ 10^4 K) gas ejected from the disc by stellar activity (the so-called galactic-fountain gas) is expected to interact with the virial-temperature (~ 10^6 K) gas of the corona.
Anderson +43 more
core +3 more sources
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding +6 more
wiley +1 more source
A Data Pre-Processing Model for the Topsis Method
TOPSIS is one of the most popular methods of multi-criteria decision making (MCDM). Its fundamental role is the establishment of chosen alternatives ranking based on their distance from the ideal and negative-ideal solution.
Kobryń Andrzej, Prystrom Joanna
doaj +1 more source
Using deep images from the Hyper Suprime-Cam (HSC) survey and taking advantage of its unprecedented weak lensing capabilities, we reveal a remarkably tight connection between the stellar mass distribution of massive central galaxies and their host dark ...
Ardila, Felipe +11 more
core +1 more source
Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco +17 more
wiley +1 more source

