Results 101 to 110 of about 18,656 (241)

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

American Journal of Medical Genetics Part A, Volume 200, Issue 11, Page 2519-2524, November 2026.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland, Amber Nakar Weinstein, Eric C. Kao, Xiaonan Zhao, Monika Weisz‐Hubshman   +4 more
wiley   +1 more source

Economic Transformation in the Digital Age: The Nexus Between Learning and Innovation

ECONOMICS
This research examines the implications of new generation digital learning technologies for the transformation of skill formation and economic outcomes under a now-ubiquitous educational environment.
Pavithra J C, Sundari V Mohana
doaj   +1 more source

The Role of Pelvic Reirradiation in the Treatment of Locally Recurrent Rectal Cancer: A Systematic Review

Biomedicines
Background: Local recurrence of rectal cancer is a challenging problem for patients and clinicians. Surgical resection is associated with good outcomes if R0 margins are achieved; however, it is often complex, requires suitable patient fitness, and is ...
Rachael E. Clifford, Sulaimaan Hannan, Hamish W. Clouston, Victoria Lavin, Claire Arthur, Paul A. Sutton   +5 more
doaj   +1 more source

Molecular Adaptations and Sex‐Biased Regulatory Pathways in Multi‐Year Diapause of the Cabbage Beetle Colaphellus bowringi: A Duration‐Resolved Transcriptomic Analysis

Ecology and Evolution, Volume 16, Issue 11, November 2026.
This study presents the first multi‐duration, sex‐stratified transcriptomic analysis of prolonged diapause in Colaphellus bowringi, revealing that extended dormancy is maintained by coordinated metabolic suppression and sustained activation of cytoprotective pathways (e.g., glutathione metabolism, autophagy).
Lili Huang, Yan Ni, Xin Ye, Xiaona Liu, Fangsen Xue, Haimin He   +5 more
wiley   +1 more source

The Sandgate Formation of the M20 Motorway near Ashford, Kent, and their correlation

, 1995
Sections in the Lower Greensand showing the top of the Hythe Formation, its junction with the Sandgate Formation of East Kent clay facies, incomplete sections in the Sandgate Formation and its junction with the Folkestone Formation, were exposed at two ...
Owen, Hugh G., Ruffell, Alastair H.; id_orcid   +1 more
core   +1 more source

CD19 CAR T Cells Expressing IL-12 Eradicate Lymphoma in Fully Lymphoreplete Mice through Induction of Host Immunity

Molecular Therapy: Oncolytics, 2018
Chimeric antigen receptor (CAR) T cell therapy represents a significant advancement in cancer therapy. Larger studies have shown ∼90% complete remission rates against chemoresistant and/or refractory CD19+ leukemia or lymphoma.
Gray Kueberuwa, Milena Kalaitsidou, Eleanor Cheadle, Robert Edward Hawkins, David Edward Gilham   +4 more
doaj   +1 more source

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan, Julia Neugebauer, Marcello Bellusci, Enrico Bertini, Garry Brown, Niklas Darin, Suzanne DeBrosse, Lucy Drexler, Stefan Drexler, Gregory M. Enns, Rebecca D. Ganetzky, Kelly Gilbert, Austin Larson, Rebecca Legi, April N. Lehman, Camile Newby, Manuel Schiff, Rachel Skeath, Peter W. Stacpoole, Sarah Thompson, Emma Watt, Saskia B. Wortmann, Jirair K. Bedoyan, Shamima Rahman   +23 more
wiley   +1 more source

vibe‐qc: An Open‐Source, General‐Purpose Electronic‐Structure Code for Molecules and Solids Developed With Generative AI

Journal of Computational Chemistry, Volume 47, Issue 28, October 30, 2026.
vibe‐qc is an open‐source, general‐purpose electronic‐structure code for molecules and solids, developed almost entirely with agentic AI under expert human direction. Molecular and periodic calculations use a common interface. Independent reference calculations form a reusable validation set.
Michael F. Peintinger
wiley   +1 more source

Propiedades psicométricas del EQ-i-M20 en estudiantes universitarios chilenos

The Brief Emotional Intelligence Inventory (EQ-i-M20) was designed to assess emotional intelligence in individuals. Its application in educational contexts allows the identification of areas for intervention and development.
Guerra Díaz, Felipe Esteban, Jorquera Gutiérrez, Ricardo, Agurto Monárdez, Pierina   +2 more
core   +1 more source

Longitudinal Follow-Up of the Psychological Well-Being of Patients with Colorectal Cancer: Final Analysis of PICO-SM

Current Oncology
PICO-SM was a prospective longitudinal study investigating the psychological impact of the COVID-19 pandemic on patients with colorectal cancer treated in a large UK tertiary cancer centre.
Konstantinos Kamposioras, Panagiotis Ntellas, Katerina Dadouli, Eleftherios Christodoulis, Marios Adamou, Daniel Anderson, Anup Shanthappa, Jacqueline Connell, Joseph Williams, Lilly Simpson, Theodora Germetaki, Michael Braun, Jorge Barriuso, Jurjees Hasan, Saifee Mullamitha, Kalena Marti, Mark Saunders, Kok Haw Jonathan Lim   +17 more
doaj   +1 more source