Results 231 to 240 of about 472,912 (287)

Semi-Mechanistic Joint Population Pharmacokinetic Modeling of the Novel Antituberculosis Drug Sorfequiline and Its Metabolite M3 in Healthy Volunteers. [PDF]

CPT Pharmacometrics Syst Pharmacol
Calderin JM, Nedelman J, Salinger DH, Vongjarudech T, Denti P, Svensson EM.   +5 more
europepmc   +1 more source

Harnessing Digital Microstructure for Simulation‐Guided Optimization of Permanent Magnets

Advanced Intelligent Discovery, EarlyView.
An experimental‐to‐computational workflow is presented that transforms experimental 3D focused ion beam‐scanning electron microscopy data into a simulation‐ready digital microstructure for multiphase functional materials. Using heavy‐rare‐earth‐free Nd–Fe–B magnets as a model system, the approach quantifies grain connectivity across complex secondary ...
Nikita Kulesh, Anton Bolyachkin, Hajime Nakamura, Tadakatsu Ohkubo, Hossein Sepehri‐Amin   +4 more
wiley   +1 more source

Parametric Analysis of Spiking Neurons in 16 nm Fin Field‐Effect Transistor Technology

Advanced Intelligent Discovery, EarlyView.
Energy efficient computing has driven a shift toward brain‐inspired neuromorphic hardware. This study explores the design of three distinct silicon neuron topologies implemented in 16 nm fin field‐Effect transistor technology. While the Axon‐Hillock design achieves gigahertz throughput, its functional fragility persists. The Morris–Lecar model captures
Logan Larsh, Raiyan Siddique, Sarah S. Sharif, Yaser Mike Banad   +3 more
wiley   +1 more source

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

Advanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed, Denis Abu Sammour, Dirk C. Hoffmann, Philipp Sievers, Tobias Bausbacher, Melissa Hahn, Yasemin Ucal, Iris Mildenberger, Christiane A. Opitz, Stefan Schmidt, Michael Platten, Oliver Wasenmüller, Wolfgang Wick, Andreas von Deimling, Tobias Kessler, Carsten Hopf   +15 more
wiley   +1 more source

Mechanistic Study on Dual-Donor Modified Distyryl-BODIPY Photosensitizers. [PDF]

Materials (Basel)
Yang Y, Wang D, Ma X, Yang J, Cheng G, Cao J.   +5 more
europepmc   +1 more source

Functionalized TiO2 Catalysts: Revolutionary Candidate for Low‐Temperature MgH2 and Prospects for Intelligent Integration

Advanced Intelligent Discovery, EarlyView.
Recent advances in TiO2 modification strategies: structure regulation and composite engineering for improved activity and functionality. TiO2 has emerged as a pivotal catalyst for enhancing MgH2, a high‐capacity solid‐state hydrogen storage material, owing to its structural versatility.
Xiaopeng Chu, Jinghao Wang, Haojie Shi, Chuanxin Peng, Jiacheng Qi, Ge Gao, Guoquan Na, Haibo Yu, Kela Xiao, Gangqiang Wu, Zhendong Yao   +10 more
wiley   +1 more source

Host availability modifies climate-based predictions of <i>Hyalomma rufipes</i> distribution with geographically variable effects of livestock mobility. [PDF]

Curr Res Parasitol Vector Borne Dis
Agboka KM, Mumo S, Meltus QJ, Baleba SBS, Hassaballa IB, Landmann T, Abdel-Rahman EM, Barreaux A, Diallo S.   +8 more
europepmc   +1 more source

Particle Swarm Optimization as a Noise‐Tolerant Strategy for High‐Entropy Alloy Research

Advanced Intelligent Discovery, EarlyView.
A customized particle swarm optimization algorithm is benchmarked against batch Bayesian optimization across four high‐entropy alloy oxygen‐reduction landscapes. While both methods locate the global optimum comparably under noise‐free conditions, Bayesian optimization’s surrogate model tends to overfit noisy data.
Ahmad Tirmidzi, Matthias Arenz, Vladislav A. Mints   +2 more
wiley   +1 more source

Project Website (M3)

Project Website ...
openaire   +1 more source