Results 11 to 20 of about 7,115 (167)

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

open access: yesHepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu   +16 more
wiley   +1 more source

Plasma Levels of K18 Fragments Do Not Correlate with Alcoholic Liver Fibrosis

open access: yesGut and Liver, 2019
Background/Aims Noninvasive markers of liver fibrosis in alcoholic liver disease (ALD) are crucial to establish early intervention. Previous studies have suggested that plasma levels of cleaved keratin-18 (K18; M30) fragments can predict the severity of ...
Viola Schlossberger   +6 more
doaj   +1 more source

A study of digital transformation and MSMEs performance from a spatial perspective: Evidence from China

open access: yesJournal of Economics and Management, 2023
Aim/purpose – Not only have micro, small, and medium enterprises (MSMEs) been regarded as a driving force of the national economy, but they have also become important in promoting innovation and entrepreneurship.
Zheng Bing   +3 more
doaj   +1 more source

Onset of heart failure determines the hepatic cell death pattern

open access: yesAnnals of Hepatology, 2011
Background and rationale. Acute and chronic heart failure (HF) may affect the liver, but the underlying mechanisms that lead to progressive liver damage are poorly understood.
Kerstin Herzer   +11 more
doaj   +1 more source

News Media Brand Equity in a New Media Environment

open access: yesEconomics and Business, 2022
Digitalisation has profoundly altered how media are distributed and audiences consume media information, reshaping the media environment and introducing new competitors to media brands.
Saulite Linda
doaj   +1 more source

Celebrity Endorsement Influence on Destination Image

open access: yesNaše Gospodarstvo, 2022
Destination image influences the tourist decision-making process, and their intention to visit, revisit and recommend. Therefore, a positive destination image is considered one of the key destination success factors.
Marković Ivana   +2 more
doaj   +1 more source

The efficacy of serum cell death biomarkers for diagnosing biliary tract cancer

open access: yesScientific Reports, 2018
In this study, we determined the efficacy of the cell death biomarker cytokeratin 18 for diagnosing biliary tract cancer (BTC). We recruited 36 patients with BTC (Malignant group) and 45 patients with benign biliary tract disease (Benign group) for this ...
Mitsuru Sugimoto   +17 more
doaj   +1 more source

Clinical Evaluation of M30 and M65 ELISA Cell Death Assays as Circulating Biomarkers in a Drug-Sensitive Tumor, Testicular Cancer

open access: yesNeoplasia: An International Journal for Oncology Research, 2008
Circulating full-length and caspase-cleaved cytokeratin 18 (CK18) are considered biomarkers of chemotherapy-induced cell death measured using a combination of the M30 and M65 ELISAs.
Esther C. de Haas   +10 more
doaj   +1 more source

The Place as a Brand. Theory and Practise of the Place Branding

open access: yesEconomics and Culture, 2023
Research purpose. The purpose of the research project was to evaluate the status of place branding as a scientific discipline and to check whether this concept has been concretised during exploration and articulation. An additional objective was to check
Adamus-Matuszyńska Anna, Dzik Piotr
doaj   +1 more source

Serum Cytokeratin 18 M30 Levels in Chronic Hepatitis B Reflect Both Phase and Histological Activities of Disease

open access: yesMediators of Inflammation, 2017
Chronic hepatitis B has highly a dynamic course with significant fluctuations of HBV-DNA and ALT impeding assessment of disease activity. New biomarkers of inflammatory versus noninflammatory stages of HBV infection are urgently needed.
Magdalena Świderska   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy