Results 211 to 220 of about 95,669 (278)

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Annual changes in crop–field composition affect crop insurance ratings

Journal of the Agricultural and Applied Economics Association, EarlyView.
Abstract This study estimates the effects of farm‐level variations in soil productivity arising from crop rotation and field selection, measured by the National Commodity Crop Productivity Index (NCCPI), on crop yield distributions and crop insurance premium rates.
Mitchell Roznik, Ashok K. Mishra, Hongqiang Yan   +2 more
wiley   +1 more source

α/Sulfonyl-γ-AApeptide foldamers mitigate Alzheimer's disease pathology by stabilizing transient helical domains in Aβ. [PDF]

Nat Commun
Liu H, Akhter F, Akhter A, Zhao X, Wang X, Yang H, Chen J, Xia X, Calcul L, He Y, Cao C, Ye L, Zhu D, Cai J.   +13 more
europepmc   +1 more source

Synthesis, Cytotoxicity, and Apoptosis‐Associated Cell Death Activity of an Isatin‐Containing Pyrimidine‐Derived Cu(II) Complex

Journal of Applied Toxicology, EarlyView.
ABSTRACT A Cu(II) complex derived from a pyrimidine with the isatin group was synthesized and tested for its cytotoxic effects on A549 lung cancer and MCF‐7 breast cancer cell lines, as well as its effects on apoptosis‐associated cell death and cell cycle regulation in A549 cells. To evaluate cytotoxicity, MTT assays were performed at 24, 48, and 72 h,
Müjgan Kesik Oktay, Cansu Topkaya, Elif Kağa, Yasin Eren, Ramazan Güp   +4 more
wiley   +1 more source

Xanomeline-Trospium Validates Muscarinic Agonism as an Effective Non-Dopaminergic Treatment for Schizophrenia. [PDF]

Int J Mol Sci
Mansour GK, Hajjar AW, Hajjar AH, Alissa A, Sukkarieh HH.   +4 more
europepmc   +1 more source

Dual Genotoxic and Antigenotoxic Effects of 3‐Benzoylcoumarins in Mammalian Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Coumarins are phenolic compounds widely recognized for their diverse pharmacological activities and have attracted increasing attention as potential chemopreventive agents. In the present study, four known 3‐benzoylcoumarin derivatives [(1), (2), (3), and (4)] were evaluated for their cytotoxic, mutagenic, and antigenotoxic effects in Chinese ...
Leticia Helena Parreira, Evelyn Pinheiro de Mendonça, Aléxia Polo Siqueira, Cleydson Finotti Cordeiro, Elkin José Torres Sierra, Rudy Bonfilio, Diogo Teixeira Carvalho, Pollyanna Francielli de Oliveira   +7 more
wiley   +1 more source

Gene network analysis predicts the primary regulators of ABA-dependent transcriptional activation and repression in Populus roots. [PDF]

PLoS Genet
Cohen D, De Freitas Pereira M, Pavlović I, Novák O, Bogeat-Triboulot MB, Cookson SJ, Hummel I.   +6 more
europepmc   +1 more source

Bioinspired Copper Sites for the Transformations of Greenhouse Gases Like Methane and Nitrous Oxide

Journal of the Chinese Chemical Society, EarlyView.
This review highlights the bioinspired catalytic systems containing copper sites that facilitate the conversions of methane and nitrous oxide to methanol and nitrogen, respectively. ABSTRACT The quest for benign catalysts for environmental remediation under ambient conditions for a sustainable future is fueling contemporary research.
Amarendra Nath Maity, Kiran Reddy Kanubaddi, Ragesh Nath Radhakrishnan, Shyue‐Chu Ke   +3 more
wiley   +1 more source

Toward Accurate RIXS Spectra at Heavy Element Edges: A Relativistic Four-Component and Exact Two-Component TDDFT Approach. [PDF]

J Chem Theory Comput
Konecny L, Dada MA, Nascimento DR, Repisky M.   +3 more
europepmc   +1 more source