Results 151 to 160 of about 3,537,313 (280)

Host Cell Protein Challenges in Antibody Processing: Insights Into Persistence and Mitigation Strategies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Persistence of HCPs remains a major purification challenge in biopharmaceutical manufacturing with direct consequences for product quality, patient safety, and regulatory compliance. Over the last two decades, deeper insights into the mechanisms driving HCP persistence have clarified why certain proteins evade removal during purification ...
Younghoon Oh, Andrew Cooke, Harshal Soni, Susan Liu, Mamadou Bah, Brianna Bellis, Laura Smith, Michael Capaldi, Nicholas Levy, Erik Wilhelm, Kristopher Barnthouse   +10 more
wiley   +1 more source

Integration of PrEP dispensing with HIV self-testing among heterosexual men in Sub-Saharan Africa: protocol for a scoping review. [PDF]

BMJ Open
Hlongwa M, Tsai AC, Choko A.
europepmc   +1 more source

Isolating T‐Cell Potent Lentiviral Vector Subpopulations through Rational Design of Nanofiber Anion‐Exchange Adsorbents

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Generation of CAR‐T cell therapies relies predominantly on lentiviral vectors (LVs). As in vivo CAR‐T trials progress, demand for larger quantities of higher‐potency LV is expected. However, primary capture by anion‐exchange chromatography (AIEX) remains a major manufacturing bottleneck from use of adsorbents not tailored to LVs, leading to ...
George Pamenter, Gyorgy Ovari, Anurag Kulkarni, Thomas Williams‐Fegredo, Carol Knevelman, Kyriacos Mitrophanous, Lee Davies, Farzad Foroutan, Matthew Townsend, Stephen Goldrick, Daniel G. Bracewell   +10 more
wiley   +1 more source

Assessing Questionable and Responsible Research Practices in Psychology Master's Theses. [PDF]

Behav Sci (Basel)
Augusteijn HEM, Wicherts JM, Sijtsma K, van Assen MALM.   +3 more
europepmc   +1 more source

What drives animal responses to high severity fire? The role of functional traits

Biological Reviews, EarlyView.
ABSTRACT Fire regimes are changing worldwide, with increases in the frequency, extent, and severity of fires posing growing risks to biodiversity. Fire severity – the degree of habitat alteration following fire – strongly influences both immediate survival and long‐term recovery of fauna.
Grace A. Vielleux, Trent D. Penman, Victoria A. Reynolds, Matthew H. Swan   +3 more
wiley   +1 more source

What do youth need to know about puberty? A scoping review protocol to identify puberty education competencies. [PDF]

PLoS One
Brault MA, Singh N, Kakkad N, Peskin M, Betori A, Laynor G, Naiser E.   +6 more
europepmc   +1 more source

Review of the fauna associated with wild and farmed mussels and oysters in the Mediterranean

Biological Reviews, EarlyView.
ABSTRACT Mussels and oysters are important ecosystem engineers which modify the physical and chemical characteristics of the environment and create habitats that support highly diverse associated communities. In the Mediterranean Sea, the native Mediterranean mussel Mytilus galloprovincialis and the European flat oyster Ostrea edulis, together the ...
Barbara Mikac, Marina Antonia Colangelo, Alessandro Tarullo, Marco Abbiati, Eugenio Fossi, Federica Costantini   +5 more
wiley   +1 more source

AI-based applications supporting informal caregivers in childhood caries prevention and management: protocol for a scoping review. [PDF]

BMJ Open
Anugrah PM, Emami E, Adiatman M, Darwita RRR.   +3 more
europepmc   +1 more source

AI‐Enabled Circular Business Model Transition for Mitigating Climate Change: A Natural Resource‐Based View Perspective on Business Strategies

Business Strategy and the Environment, EarlyView.
ABSTRACT The role of artificial intelligence (AI) in achieving sustainability goals has garnered attention in academic literature. While AI has been argued to be crucial in addressing circularity challenges, organizations face challenges in configuring a business model.
Jian Wang, Sanjay Chaudhary, Muhammad Mustafa Kamal, Salwa Saleh Almasabi, Sándor Remsei   +4 more
wiley   +1 more source

Stages and costs of processing donated corneas for transplantation in eye banks: a scoping review. [PDF]

Cell Tissue Bank
Menezes BKA, Ferreira Junior MA, da Silva AM, Fernandes GE, Mota FM, Frota OP, da Silva Martins MD.   +6 more
europepmc   +1 more source