Results 41 to 50 of about 1,169,127 (318)
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Using Platelet-Rich Fibrin to Remove Graphite Tattoos May Yield Excellent Long-Term Result
Graphite tattoos are rarely reported because they are mainly caused by an accidental injury or habits during childhood that cause a pencil to penetrate the oral mucosa.
Young Joon Cho +3 more
doaj +1 more source
A BP Network Control Approach for QoS-Aware MAC in Cloud Robotics [PDF]
The basic idea of Cloud Robotics is dynamically uploading the compute-intensive applications to the cloud, which greatly enhances the intelligence of robots for the high processing and parallel ability of cloud.
doaj +1 more source
DECREASING THE RA COLLISION IMPACT FOR MASSIVE NB-IOT IN 5G WIRELESS NETWORKS
To satisfy the gigantic need for Internet of things (IoT) applications, the third-generation partnership project (3GPP) has revealed the narrowband IoT (NB-IoT) standard. In any case, collisions in the radio access channel of NB-IoT can be extreme due to
Bilal Rabah Al-Doori, Ahmed Zurfi
doaj +1 more source
A Flexible and Fast Event-Driven Simulator for wireless MAC protocols [PDF]
Many multiple-access (MAC) protocols have been or are being proposed for wireless networks. As most of these multiple-access protocols are designed for specific applications (such as telephony) and analyzed accordingly, the analysis results can not ...
Havinga, Paul J.M. +1 more
core +5 more sources
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
On Achievable Rate Region of Multiple Coordinated Multiple Access Channels [PDF]
Coordination between two or more multiple access channel (MAC) receivers can enlarge the achievable rate region of the whole system. This paper focuses on coordination by sharing the codebooks of the users between the receivers of MACs.
Heliot, Fabién +2 more
core +1 more source
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Daisuke Fukushi,1 Keigo Murakami,2 Yuji Watanabe,3 Norihiko Sugimoto,4 Hirotsugu Uehara,4 Masafumi Seki5 1Division of Gastroenterology, Tohoku Medical and Pharmaceutical University Hospital, Sendai City, Miyagi, Japan; 2Division of Pathology, Tohoku ...
Fukushi D +5 more
doaj

