Results 51 to 60 of about 97,227 (255)

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

Advanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang, Jiaxin Tian, Xiaolong Zhu, Xiao Li, Xiangshu Qiu, Yuanyuan Li, Ben Zhong Tang, Ning Shi   +7 more
wiley   +1 more source

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

Advanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury, Xuanyi Lin, Peter D. Rios, Christopher Olker, Eun Joo Song, Alejandra Cobos Perez, Cody Fell, Daisy Lopez, Ira Joshi, Hafsa Nasir, Cecelia Curtis, Danna Muringi, Kaiyuan Wang, José Oberholzer, Fred W. Turek, Isaac B. Hilton, Jonathan Rivnay, Martha Hotz Vitaterna, Omid Veiseh   +18 more
wiley   +1 more source

A case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury

Ibrain, 2023
Decubitus ulcers are a common spinal cord injury (SCI) complication that puts patients' lives in danger and has emerged as a more prevalent issue in modern clinical rehabilitation and care.
Yong‐Min Niu, Hao‐Yue Qin, Jin‐Xiang Liu, Xin‐Yi Li, An‐Su Wang, Ling‐Xia Sun, Ni‐Jiao Huang, Chang‐Wei Yang, Yu Cao, Tao Bai, Yang Lan, Sheng Liu, Hao Yuan   +12 more
doaj   +1 more source

VDJ Gene Usage in IgM Repertoires of Rhesus and Cynomolgus Macaques

Frontiers in Immunology, 2022
Macaques are frequently used to evaluate candidate vaccines and to study infection-induced antibody responses, requiring an improved understanding of their naïve immunoglobulin (IG) repertoires.
Mark Chernyshev, Mateusz Kaduk, Martin Corcoran, Gunilla B. Karlsson Hedestam   +3 more
doaj   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina

Journal of Extracellular Biology, 2022
Extracellular vesicles (EVs) have potential in disease treatment since they can be loaded with therapeutic molecules and engineered for retention by specific tissues.
Tom Driedonks, Linglei Jiang, Bess Carlson, Zheng Han, Guanshu Liu, Suzanne E. Queen, Erin N. Shirk, Olesia Gololobova, Zhaohao Liao, Lyle H. Nyberg, Gabriela Lima, Liliia Paniushkina, Marta Garcia‐Contreras, Kayla Schonvisky, Natalie Castell, Mitchel Stover, Selena Guerrero‐Martin, Riley Richardson, Barbara Smith, Vasiliki Mahairaki, Charles P. Lai, Jessica M. Izzi, Eric K. Hutchinson, Kelly A. M. Pate, Kenneth W. Witwer   +24 more
doaj   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Anopheles sundaicus Mosquitoes as Vector for Plasmodium knowlesi, Andaman and Nicobar Islands, India

Emerging Infectious Diseases, 2019
Using PCR and sequencing, we found Plasmodium knowlesi in the malaria vector Anopheles sundaicus mosquito collected from Katchal Island in the Andaman and Nicobar Islands, India.
Pachalil Thiruvoth Vidhya, Ittoop Pulikkottil Sunish, Anwesh Maile, Ali Khan Zahid   +3 more
doaj   +1 more source

Maracas for Macaca? Evaluation of three potential enrichment objects in two species of zoo-housed macaques

, 2000
One group each of Barbary macaques and stumptailed macaques, both zoo-housed, received hard replica fruits in three experimental conditions: as empty (“unresponsive”) objects, as maracas which rattled when manipulated (“simple ...
Vick, Sarah-Jane, Young, R, Anderson, James, Anderson, J, Young, Robert, Vick, S   +5 more
core   +1 more source

Neural Processes Underlying Tool Use in Humans, Macaques, and Corvids

Frontiers in Psychology, 2020
It was thought that tool use in animals is an adaptive specialization. Recent studies, however, have shown that some non-tool-users, such as rooks and jays, can use and manufacture tools in laboratory settings.
María J. Cabrera-Álvarez, Nicola S. Clayton   +1 more
doaj   +1 more source