Results 161 to 170 of about 45,340 (263)

Pericoronary adipose tissue radiomics enhances prediction of major adverse cardiovascular events beyond CCTA-derived functional parameters in coronary atherosclerosis. [PDF]

Front Cardiovasc Med
Wang Z, Wu Z, Cao M, Zhao L, Zhang G, Wu S, Zhang X, Ning J, Zhang Y, Wang J, Yin L, Wang Q, Xu Z.   +12 more
europepmc   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source

The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, restores blood–brain barrier integrity in a human stem cell‐based model of ischaemic stroke

British Journal of Pharmacology, EarlyView.
Ischaemic stroke is characterised by acute cerebrovascular occlusion and blood–brain barrier (BBB) breakdown. Our results indicated that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) ameliorated the loss of BBB integrity, changed the morphology of brain endothelial cells, increased the level of basement membrane and ...
Anikó Szecskó, Koppány Párdi, Zuhao Cui, Gergő Porkoláb, Zsófia Hoyk, Csilla Kovács, Janet F. Adegbite, Virág Fodor, Nárcisz M. Cser, László Dér, Krisztina Nagy, Csilla Sajben, Roland Tengölics, Mária A. Deli, Szilvia Veszelka   +14 more
wiley   +1 more source

Interpretable Machine Learning Framework for Predicting Major Adverse Cardiovascular Events in Rheumatoid Arthritis Using Electronic Health Records: Multicenter Cohort Study. [PDF]

JMIR Form Res
Chiang WC, Lin GL, Chang YS, Liu YC, Huang CW, Nguyen PA, Hsu JC, Liou DM, Yang HC.   +8 more
europepmc   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, EarlyView.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

Maternal and Paternal Extended Family Support Among Children in Foster Care: Associations With Internalizing Symptoms Trajectories

Child &Family Social Work, EarlyView.
ABSTRACT Prior work suggests that children who are supported by their extended family kinship network experience fewer internalizing problems, with most of this support coming from the maternal side of the family. However, less is known about the unique contributions to well‐being associated with maternal versus paternal extended family support among ...
Kimberly R. Davenport, Taira Masuda, Scott C. Leon   +2 more
wiley   +1 more source

Cardiometabolic and RAAS-Targeted Therapy in Thoracic Aortic Aneurysm: Propensity-Matched Associations with Survival and Major Cardiovascular Events. [PDF]

Med Sci (Basel)
Abdul Nabi H, Dreher L, Al Osta S, Shamoun FE.   +3 more
europepmc   +1 more source

Disrupting the Child Welfare Participation Paradigm: A Contextual, Relational, Embedded and Pragmatic Approach

Child &Family Social Work, EarlyView.
ABSTRACT Child and parent participation is fundamental to effective child welfare practice. Legislative imperatives assert the right to participate, but in a child welfare context, participation is complex and risks becoming rhetorical. This paper, based on a conceptual synthesis built from second person action research and a narrative review, explores
Jeri L. Damman, Teresa Bertotti, Diletta Mauri, Gillian Ruch, Karen Winter   +4 more
wiley   +1 more source

Impact of Glucagon-like Peptide-1 Receptor Agonists and Sodium-Glucose Cotransporter-2 Inhibitors on Post-liver Transplant New-onset Major Adverse Cardiovascular Events, Graft Failure, Renal Outcome, and Mortality. [PDF]

Transplant Direct
Kosako Yost KC, Ghai MB, Aboona M, Ali Q, Rangan P, Gomez P, Nathan R, Wong M, Wijarnpreecha K, Nevah Rubin MI, Fallon M, Han MAT.   +11 more
europepmc   +1 more source

Evaluating the use of taxonomy in the IUCN Red List

Conservation Biology, EarlyView.
Abstract Taxonomy defines the units that conservationists strive to preserve for future generations. However, the discovery of new species and the taxonomic revision of existing species affect conservation efforts. Despite the importance of taxonomy for a species’ conservation, there is currently no overview of how those leading species extinction risk
Stephen T. Garnett, Claire E. Johnston, Phil Bowles, Les Christidis, Stijn Conix, J. W. Duckworth, Aaron Lien, Frank E. Zachos, Joeri Witteveen   +8 more
wiley   +1 more source