Results 21 to 30 of about 184,141 (196)

Identification of semen traces at a crime scene through Raman spectroscopy and machine learning

Scientific Reports
Biological fluid stains can be instrumental in solving crimes. Identification of semen can help reconstruct events in sexual assault cases and identify suspects via DNA profiling.
Alexey V. Borisov, Mikhail S. Snegerev, Sonivette Colón-Rodríguez, Marisia A. Fikiet, Igor K. Lednev, Yury V. Kistenev   +5 more
doaj   +1 more source

Diffusion models for 3D generation: A survey

Computational Visual Media
Denoising diffusion models have demonstrated tremendous success in modeling data distributions and synthesizing high-quality samples. In the 2D image domain, they have become the state-of-the-art and are capable of generating photo-realistic images with ...
Chen Wang, Hao-Yang Peng, Ying-Tian Liu, Jiatao Gu, Shi-Min Hu   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Large language model-assisted multi-objective optimization for an integrated multimodal e-mobility platform

Transportation Research Interdisciplinary Perspectives
As urban transportation evolves, shared e-mobility is increasingly recognized as a socio-technical system shaping urban equity, social inclusion, and mobility behaviour.
Yue Ding, Mayug Maniparambil, Noel E. O’Connor, Mingming Liu   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Machine Learning Techniques for Prognosis Estimation and Knowledge Discovery From Lab Test Results With Application to the COVID-19 Emergency

IEEE Access, 2023
AI and Machine Learning (ML) offer powerful tools to support clinical decision making in emergency situations such as the COVID-19 pandemic. In this context, the application of ML requires to design predictive systems that have adequate accuracy and can ...
Alfonso Emilio Gerevini, Roberto Maroldi, Matteo Olivato, Luca Putelli, Ivan Serina   +4 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Pragmatic Study of Botnet Attack Detection In An IoT Environment [PDF]

E3S Web of Conferences
A comprehensive search for primary research published between 2014 and 2023 was carried across several databases. Studies that describe the application of machine learning (ML) and deep learning techniques for if they was carried out across several ...
Vennapureddy Rajasree, Srinivasulu T.
doaj   +1 more source