Results 61 to 70 of about 1,682 (264)

ASSESSMENT OF THE IMPACT EXCITATION CURRENT PARAMETERES OF THE SYNCHRONOUS GENERATOR ON THE INDICATORS OF QUALITY OF THE PRODUCED ELECTRIC ENERGY

Вестник Северо-Кавказского федерального университета, 2022
The article discusses issues related to the impact of excitation current parameters of a synchronous machine and of possible emergencies in the field windings on the level of the quality of the generated electrical energy.
Pavel Zvada, Maxim Plyashko, Andrey Mironov   +2 more
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

MACHINE-TRANSFORMER UNITS FOR WIND TURBINES

Electrical Engineering & Electromechanics, 2016
Background. Electric generators of wind turbines must meet the following requirements: they must be multi-pole; to have a minimum size and weight; to be non-contact, but controlled; to ensure the maximum possible output voltage when working on the power supply system. Multipole and contactless are relatively simply realized in the synchronous generator
Panchenko, V. I., Tsyplenkov, D. V., Grebeniuk, A. M., Kyrychenko, M. S., Bobrov, O. V.   +4 more
openaire   +5 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Experimental analysis for star and open-end stator winding structures of IM

Power Electronics and Drives
This article focuses on the scalar control of four induction machine structures: the conventional induction machine, the double-star machine, the open-ended stator winding machine and the dual open-end stator winding machine.
Nayli Abdelmonoem, Guizani Sami, Ben Ammar Faouzi   +2 more
doaj   +1 more source

Effect of Winding Phase-Shifting on Low-Space-Harmonic Design in Six-Phase Permanent-Magnet Synchronous Machine

CES Transactions on Electrical Machines and Systems
Fractional-slot concentrated windings (FSCWs) are widely utilized in six-phase fault-tolerant permanent-magnet synchronous machines (PMSMs). However, FSCWs cause abundant space harmonics of stator magnetomotive force (MMF) and increase the losses of the ...
Zihang Yuan, Yi Sui, Ping Zheng, Luming Cheng, Wei Liu, Jingang Bai   +5 more
doaj   +1 more source