Results 161 to 170 of about 13,240 (266)

Towards Ultra-Precision Manufacturing: Advancements and Future Trends in Energy Field-Assisted Jet Machining. [PDF]

Micromachines (Basel)
He Y, Chen T, Man X, Su T.
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Advancing sustainable machining of inconel 718 through nanoparticle-enhanced coconut oil and RSM-GA optimization. [PDF]

Sci Rep
Almomani O, Rajput V, Rao ACU, Samantaray S, Patil N, Singh R, Naidu BVV, Sahani M, Bhowmik A, Abate L.   +9 more
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Study on D6AC Steel PCBN Hard Turning and Optimization. [PDF]

Materials (Basel)
Liu Y, Huang S, Li R, Cui Z, Zhang Y, Liu C.   +5 more
europepmc   +1 more source

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

Arthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein, Jennifer L. F. Lee, Evelyne Vinet, Arielle Mendel, Christian A. Pineau, Fares Kalache, Louis‐Pierre Grenier, Sasha Bernatsky   +7 more
wiley   +1 more source

Effect of Cutting Conditions on Roughness and Cutting Force When Machining a Freeform Surface with Barrel Tools. [PDF]

Materials (Basel)
Reznicek M, Horava C, Zajicek J, Ovsik M.   +3 more
europepmc   +1 more source

Micro Machining with General Purpose Machining Center

Journal of the Japan Society for Precision Engineering, 2019
openaire   +2 more sources

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source

High-Quality and High-Efficiency Fabrication of Microlens Array by Rotary Profile Cutting Method. [PDF]

Micromachines (Basel)
Gao L, Sun X, Yu Q, Wang Y, Uddin MN, Duan R, Wang G, Zhou Z, Xie Q, Sun T, Zhou T.   +10 more
europepmc   +1 more source