Results 111 to 120 of about 4,569,282 (327)

Octree-based production of near net shape components [PDF]

, 2008
Near net shape (NNS) manufacturing refers to the production of products that require a finishing operation of some kind. NNS manufacturing is important because it enables a significant reduction in: machining work, raw material usage, production time ...
Corney, J.R., Davies, J.B.C., Lim, T., Medellin, H., Ritchie, J.M.   +4 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

An Intelligent Process Planning Method for Shaft Parts Based on Multi-Graph Fusion: From Feature Recognition to Process Route Generation

Applied Sciences
Conventional process planning methods—typically driven by rules or expert heuristics—struggle to handle complex structural components, often yielding low efficiency and limited optimization.
Zhenfeng Dai, Zhi Shou, Shuangling Ma, Xiaobo Peng   +3 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

High-speed Fabrication of Micro-channels using Line-based Laser Induced Plasma Micromachining (L-LIPMM) [PDF]

, 2013
Micro-texturing of surfaces has various applications that often involve texturing over large (macro-scale) areas with high precision and resolution. This demands scalability and speed of texturing while retaining feature sizes on the order of a few ?m.
Cao, Jian, Ehmann, Kornel, Malhotra, Rajiv, Saxena, Ishan   +3 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Knowledge-Based Manufacturing: Management and Deployment of Manufacturing Rules through Product Lifecycle Management Systems

Aerospace, 2019
In manufacturing companies, computer-aided design (CAD)/computer-aided manufacturing (CAM) feature-based approaches have been developed for faster numerical control (NC) programming.
Angelo Corallo, Manuela Marra, Claudio Pascarelli   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Automatic Generation of Machining Sequence for Machined Parts Using Machining Features

Journal of the Korea Academia-Industrial cooperation Society, 2016
As 3D solid modeling prevails, a range of applications have become possible and intensive research on the integration of CAD/CAM has been conducted. As a consequence, methods to recognize the machining features from CAD models have been developed. On the other hand, generating a machining sequence using the machining features is still a problem due to ...
Yoonhwan Woo, Sangwook Kang
openaire   +2 more sources