Results 121 to 130 of about 4,569,282 (327)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

An Agent-Based Method for Feature Recognition and Path Optimization of Computer Numerical Control Machining Trajectories

Sensors
In recent years, artificial intelligence technology has seen increasingly widespread application in the field of intelligent manufacturing, particularly with deep learning offering novel methods for recognizing geometric shapes with specific features. In
Purui Li, Meng Chen, Chuanhao Ji, Zheng Zhou, Xusheng Lin, Dong Yu   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Optimization of roughing operations in cnc machining for rapid manufacturing processes [PDF]

, 2013
This paper presents a method for optimizing roughing operations in CNC machining particularly for parts production through a subtractive rapid manufacturing process. The roughing operation in machining is primarily used to remove the bulk of the material
Case, Keith, Osman, Muhammed, Watts, Darren   +2 more
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Predictable feature analysis and slow feature machines

Um interaktive Aufgaben mit Slow Feature Analysis (SFA) und ähnlichen Methoden zu behandeln, wird Predictable Feature Analysis (PFA) entwickelt - ein Algorithmus, der möglichst vorhersagbare Komponenten aus hochdimensionalen Eingabedaten extrahiert. Mit Hilfe dieser kann ein System lokal gesteuert werden und durch Einführung von "Slow Feature Machines"
openaire   +2 more sources

Feature-Based Machining Using Macro

, 2012
{"references": ["Peter Smid, CNC Programming Handbook: A Comprehensive Guide to\nPractical CNC Programming, Industrial Press, 2003.", "Bor-Tyng Sheen and Chun-Fong You, \"Machining feature recognition\nand tool-path generation for 3-axis CNC milling,\" Computer-Aided\nDesign, vol. 38, pp. 553-562, 2006.", "X.W. Xu and S.T.
M. Razak, A. Jusoh, A. Zakaria
openaire   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Machining of Lenticular Lens Silicon Molds with a Combination of Laser Ablation and Diamond Cutting

Micromachines, 2019
Lenticular lenses are widely used in the three-dimensional display industry. Conventional lenticular lens components are made of plastics that have low thermal stability.
Jide Han, Lihua Li, Wingbun Lee
doaj   +1 more source

A novel architecture for a reconfigurable micro machining cell [PDF]

, 2008
There is a growing demand for machine tools that are specifically designed for the manufacture of micro-scale components. Such machine tools are integrated into flexible micro-manufacturing systems.
Al-Sharif, R, Makatsoris, C, Sadik, S
core