Results 141 to 150 of about 4,569,282 (327)

Automation of technological preparation of metal working on heavy machine tools [PDF]

open access: yes, 2018
The programs for selection of the cutting tools construction and cutting regimes are working in unrestricted surroundings elaborate of addition SharpDevelop in language C#.
Klymenko, G. P., Kvashnin, V. V.
core  

Surface Analysis of OFE-Copper X-Band Accelerating Structures and Possible Correlation to RF Breakdown Events

open access: yes, 2003
X-band accelerator structures meeting the Next Linear Collider (NLC) design requirements have been found to suffer vacuum surface damage caused by radio frequency (RF) breakdown, when processed to high electric-field gradients.
E. L. Garwin   +8 more
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Real time integration of user preferences into virtual prototypes [PDF]

open access: yes, 2009
Within new product development (NPD), both virtual prototypes and physical prototypes play important roles in creating, testing and modifying designs.
Campbell, R Ian, Liu, Bingjian
core  

Highly interacting machining feature recognition via small sample learning

open access: yesRobotics Comput. Integr. Manuf., 2022
Peizhi Shi   +4 more
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Monolithic folded pendulum accelerometers for seismic monitoring and active isolation systems [PDF]

open access: yes, 2006
A new class of very low noise low-frequency force-balance accelerometers is presented. The device has been designed for advanced mirror isolation systems of interferometric gravitational wave detectors.
Bertolini, Alessandro   +3 more
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

齿轮齿面的分形模拟

open access: yesJixie chuandong, 2014
Gear tooth surfaces are not absolutely smooth,but have roughness and waviness produced with all machining techniques.For the grinded gear tooth surface,its surface roughness is anisotropic in the direction of machining path and the perpendicular ...
冯兰兰, 汪久根
doaj  

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